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Finding the exosome.

Overview of attention for book
Attention for Chapter 8: RNA Exosome
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Chapter title
RNA Exosome
Chapter number 8
Book title
RNA Exosome
Published in
Advances in experimental medicine and biology, January 2010
DOI 10.1007/978-1-4419-7841-7_8
Pubmed ID
Book ISBNs
978-1-4419-7840-0, 978-1-4419-7841-7
Authors

Butler JS, Mitchell P, Butler, J Scott, Mitchell, Phil, Butler, J. Scott, J. Scott Butler, Phil Mitchell

Abstract

This chapter reviews the present state of knowledge on the activity of enzymes that function with the RNA exosome in the nucleus. In this compartment, the exosome interacts physically and functionally with the exoribonuclease Rrp6 and several cofactors, most prominently Rrp47 and the TRAMP complex. These interactions decide the fate of RNA precursors from transcription through the formation of mature ribonucleoprotein particles (RNPs) and the export of the RNPs to the cytoplasm. The nuclear exosome catalyzes the formation of the mature 3' ends of many of these RNAs, but in other cases degrades the RNAs to mononucleotides. Cofactors such as Mpp6, TRAMP and the Nrd1/Nab3 complex play important roles in determining the outcome of the interaction of RNPs with the nuclear exosome. The details that govern the specificity of these decisions remain a rich source for future investigation.

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The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 65 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 2 3%
Unknown 63 97%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 18 28%
Researcher 8 12%
Student > Master 8 12%
Student > Bachelor 6 9%
Professor 4 6%
Other 8 12%
Unknown 13 20%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 25 38%
Agricultural and Biological Sciences 21 32%
Medicine and Dentistry 3 5%
Neuroscience 1 2%
Unspecified 1 2%
Other 0 0%
Unknown 14 22%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 24 April 2016.
All research outputs
#15,690,772
of 23,316,003 outputs
Outputs from Advances in experimental medicine and biology
#2,540
of 4,992 outputs
Outputs of similar age
#136,497
of 166,049 outputs
Outputs of similar age from Advances in experimental medicine and biology
#52
of 88 outputs
Altmetric has tracked 23,316,003 research outputs across all sources so far. This one is in the 22nd percentile – i.e., 22% of other outputs scored the same or lower than it.
So far Altmetric has tracked 4,992 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.2. This one is in the 37th percentile – i.e., 37% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 166,049 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 8th percentile – i.e., 8% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 88 others from the same source and published within six weeks on either side of this one. This one is in the 34th percentile – i.e., 34% of its contemporaries scored the same or lower than it.