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Depression and anxiety in individuals with amyotrophic lateral sclerosis: a systematic review

Overview of attention for article published in Trends in Psychiatry and Psychotherapy, March 2016
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Title
Depression and anxiety in individuals with amyotrophic lateral sclerosis: a systematic review
Published in
Trends in Psychiatry and Psychotherapy, March 2016
DOI 10.1590/2237-6089-2015-0030
Pubmed ID
Authors

Tatiana Lins Carvalho, Lilian Maria Sanguinett de Almeida, Camila Maria Araújo Lorega, Mirella Francyne Oliveira Barata, Maria Lúcia Brito Ferreira, Paulo Roberto de Brito-Marques, Carolina da Cunha Correia

Abstract

Introduction Studies assessing symptoms of depression and anxiety in individuals with amyotrophic lateral sclerosis (ALS) have reported contradictory results. The objective of this systematic review is to identify the prevalence of these mood disorders in the literature. Methods We searched the PubMed, HighWire, MEDLINE, SciELO, LILACS and ScienceDirect databases. Literature was selected for review in two stages, according to eligibility criteria. The first stage involved searching databases and checking titles and abstracts. The second step consisted of reading complete articles and excluding those that did not meet the inclusion criteria. The inclusion criteria were articles written in Portuguese, English or Spanish, published in the last five years and involving people with ALS diagnosed according to the El Escorial criteria. Results The database searches returned a total of 1,135 titles and abstracts and then 1,117 of these were excluded. Eighteen articles were selected for review. The 12-item Amyotrophic Lateral Sclerosis Depression Inventory (ADI-12) was the only instrument designed specifically to assess depression in ALS, but it was only used in three studies. No instruments specifically designed for anxiety in ALS were used. A large number of studies found presence and slight increase of anxiety disorders. There was considerable large variation in the results related to depressive disorders, ranging from moderate depression to an absence of symptoms. Conclusions Patients with ALS may exhibit symptoms of depression and anxiety at different levels, but there is a need for studies using specific instruments with larger samples in order to ascertain the prevalence of symptoms in ALS and the factors associated with it.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 26 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 26 100%

Demographic breakdown

Readers by professional status Count As %
Professor 2 8%
Student > Ph. D. Student 1 4%
Professor > Associate Professor 1 4%
Unknown 22 85%
Readers by discipline Count As %
Nursing and Health Professions 1 4%
Materials Science 1 4%
Medicine and Dentistry 1 4%
Unknown 23 88%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 06 April 2016.
All research outputs
#20,656,820
of 25,374,917 outputs
Outputs from Trends in Psychiatry and Psychotherapy
#199
of 277 outputs
Outputs of similar age
#234,344
of 315,378 outputs
Outputs of similar age from Trends in Psychiatry and Psychotherapy
#4
of 5 outputs
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