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Systems Biology of RNA Binding Proteins

Overview of attention for book
Attention for Chapter 1: Evolutionary Conservation and Expression of Human RNA-Binding Proteins and Their Role in Human Genetic Disease.
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Chapter title
Evolutionary Conservation and Expression of Human RNA-Binding Proteins and Their Role in Human Genetic Disease.
Chapter number 1
Book title
Systems Biology of RNA Binding Proteins
Published in
Advances in experimental medicine and biology, January 2014
DOI 10.1007/978-1-4939-1221-6_1
Pubmed ID
Book ISBNs
978-1-4939-1220-9, 978-1-4939-1221-6
Authors

Stefanie Gerstberger, Markus Hafner, Manuel Ascano, Thomas Tuschl, Gerstberger, Stefanie, Hafner, Markus, Ascano, Manuel, Tuschl, Thomas

Editors

Gene W. Yeo

Abstract

RNA-binding proteins (RBPs) are effectors and regulators of posttranscriptional gene regulation (PTGR). RBPs regulate stability, maturation, and turnover of all RNAs, often binding thousands of targets at many sites. The importance of RBPs is underscored by their dysregulation or mutations causing a variety of developmental and neurological diseases. This chapter globally discusses human RBPs and provides a brief introduction to their identification and RNA targets. We review RBPs based on common structural RNA-binding domains, study their evolutionary conservation and expression, and summarize disease associations of different RBP classes.

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The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 131 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 1 <1%
Sweden 1 <1%
Italy 1 <1%
Unknown 128 98%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 28 21%
Researcher 23 18%
Student > Master 19 15%
Student > Bachelor 14 11%
Student > Doctoral Student 6 5%
Other 16 12%
Unknown 25 19%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 46 35%
Agricultural and Biological Sciences 32 24%
Medicine and Dentistry 11 8%
Chemistry 3 2%
Pharmacology, Toxicology and Pharmaceutical Science 2 2%
Other 6 5%
Unknown 31 24%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 11 September 2014.
All research outputs
#14,658,020
of 22,763,032 outputs
Outputs from Advances in experimental medicine and biology
#2,238
of 4,927 outputs
Outputs of similar age
#180,790
of 305,294 outputs
Outputs of similar age from Advances in experimental medicine and biology
#71
of 138 outputs
Altmetric has tracked 22,763,032 research outputs across all sources so far. This one is in the 35th percentile – i.e., 35% of other outputs scored the same or lower than it.
So far Altmetric has tracked 4,927 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.0. This one has gotten more attention than average, scoring higher than 54% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 305,294 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 40th percentile – i.e., 40% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 138 others from the same source and published within six weeks on either side of this one. This one is in the 48th percentile – i.e., 48% of its contemporaries scored the same or lower than it.