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Mendeley readers
Attention Score in Context
| Title |
Antioxidant activity and peroxidase inhibition of Amazonian plants extracts traditionally used as anti-inflammatory
|
|---|---|
| Published in |
BMC Complementary Medicine and Therapies, February 2016
|
| DOI | 10.1186/s12906-016-1061-9 |
| Pubmed ID | |
| Authors |
Fabiano S. de Vargas, Patricia D. O. Almeida, Ana Paula A. de Boleti, Maria M. Pereira, Tatiane P. de Souza, Marne C. de Vasconcellos, Cecilia Veronica Nunez, Adrian M. Pohlit, Emerson S. Lima |
| Abstract |
The Amazon is the largest rainforest in the world and is home to a rich biodiversity of medicinal plants. Several of these plants are used by the local population for the treatment of diseases, many of those with probable anti-inflammatory effect. The aim of the present investigation was to evaluate the in vitro antioxidant and anti-peroxidases potential of the ethanol extracts of five plants from the Brazilian Amazon (Byrsonima japurensis, Calycophyllum spruceanum, Maytenus guyanensis, Passiflora nitida and Ptychopetalum olacoides). DPPH, ABTS, superoxide anion radical, singlet oxygen and the β-carotene bleaching methods were employed for characterization of free radical scavenging activity. Also, total polyphenols were determined. Antioxidant activities were evaluated using murine fibroblast NIH3T3 cell. Inhibition of HRP and MPO were evaluated using amplex red® as susbtract. The stem bark extracts of C. spruceanum and M. guyanensis provided the highest free radical scavenging activities. C. spruceanum exhibited IC50 = 7.5 ± 0.9, 5.0 ± 0.1, 18.2 ± 3.0 and 92.4 ± 24.8 μg/mL for DPPH(•), ABTS(+•), O2 (-•) and (1)O2 assays, respectively. P. olacoides and C. spruceanum extracts also inhibited free radicals formation in the cell-based assay. At a concentration of 100 μg/mL, the extracts of C. spruceanum, B. japurensis inhibited horseradish peroxidase by 62 and 50 %, respectively. C. spruceanum, M. guyanensis, B. japurensis also inhibited myeloperoxidase in 72, 67 and 56 %, respectively. This work supports the folk use these species that inhibited peroxidases and exhibited significant free radical scavenging and antioxidant activities what can be related to treatment of inflammation. |
Mendeley readers
The data shown below were compiled from readership statistics for 107 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Germany | 1 | <1% |
| Unknown | 106 | 99% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Bachelor | 20 | 19% |
| Student > Master | 17 | 16% |
| Researcher | 15 | 14% |
| Other | 6 | 6% |
| Student > Doctoral Student | 5 | 5% |
| Other | 18 | 17% |
| Unknown | 26 | 24% |
| Readers by discipline | Count | As % |
|---|---|---|
| Chemistry | 19 | 18% |
| Agricultural and Biological Sciences | 17 | 16% |
| Pharmacology, Toxicology and Pharmaceutical Science | 12 | 11% |
| Medicine and Dentistry | 10 | 9% |
| Biochemistry, Genetics and Molecular Biology | 9 | 8% |
| Other | 12 | 11% |
| Unknown | 28 | 26% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 08 April 2016.
All research outputs
#20,318,358
of 22,860,626 outputs
Outputs from BMC Complementary Medicine and Therapies
#2,980
of 3,634 outputs
Outputs of similar age
#251,371
of 297,543 outputs
Outputs of similar age from BMC Complementary Medicine and Therapies
#54
of 69 outputs
Altmetric has tracked 22,860,626 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.
So far Altmetric has tracked 3,634 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 8.5. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 297,543 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 69 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.