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A comparison of two distinct murine macrophage gene expression profiles in response to Leishmania amazonensis infection

Overview of attention for article published in BMC Microbiology, January 2012
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (86th percentile)
  • High Attention Score compared to outputs of the same age and source (90th percentile)

Mentioned by

blogs
1 blog

Citations

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13 Dimensions

Readers on

mendeley
54 Mendeley
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Title
A comparison of two distinct murine macrophage gene expression profiles in response to Leishmania amazonensis infection
Published in
BMC Microbiology, January 2012
DOI 10.1186/1471-2180-12-22
Pubmed ID
Authors

Christian M Probst, Rodrigo A Silva, Juliana P B Menezes, Tais F Almeida, Ivana N Gomes, Andréia C Dallabona, Luiz S Ozaki, Gregory A Buck, Daniela P Pavoni, Marco A Krieger, Patrícia S T Veras

Abstract

The experimental murine model of leishmaniasis has been widely used to characterize the immune response against Leishmania. CBA mice develop severe lesions, while C57BL/6 present small chronic lesions under L. amazonensis infection. Employing a transcriptomic approach combined with biological network analysis, the gene expression profiles of C57BL/6 and CBA macrophages, before and after L. amazonensis infection in vitro, were compared. These strains were selected due to their different degrees of susceptibility to this parasite.

Mendeley readers

The data shown below were compiled from readership statistics for 54 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Brazil 4 7%
France 1 2%
Germany 1 2%
Unknown 48 89%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 13 24%
Student > Master 10 19%
Researcher 8 15%
Student > Postgraduate 6 11%
Student > Doctoral Student 5 9%
Other 10 19%
Unknown 2 4%
Readers by discipline Count As %
Agricultural and Biological Sciences 31 57%
Immunology and Microbiology 7 13%
Biochemistry, Genetics and Molecular Biology 7 13%
Medicine and Dentistry 2 4%
Veterinary Science and Veterinary Medicine 1 2%
Other 4 7%
Unknown 2 4%

Attention Score in Context

This research output has an Altmetric Attention Score of 6. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 21 March 2012.
All research outputs
#593,361
of 3,684,317 outputs
Outputs from BMC Microbiology
#104
of 747 outputs
Outputs of similar age
#9,959
of 73,201 outputs
Outputs of similar age from BMC Microbiology
#2
of 21 outputs
Altmetric has tracked 3,684,317 research outputs across all sources so far. Compared to these this one has done well and is in the 83rd percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 747 research outputs from this source. They receive a mean Attention Score of 2.8. This one has done well, scoring higher than 86% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 73,201 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 86% of its contemporaries.
We're also able to compare this research output to 21 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 90% of its contemporaries.