Orally bioavailable glutamine antagonist prodrug JHU-083 penetrates mouse brain and suppresses the growth of MYC-driven medulloblastoma

Overview of attention for article published in Translational Oncology, July 2019

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JHU-083

Cited by user Meodipt on 16 Aug 2023

JHU-083 is an experimental drug which acts as a glutaminase inhibitor. It is a prodrug which is cleaved in vivo to the active form 6-diazo-5-oxo- L -norleucine.

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