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Drug Safety Evaluation

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Cover of 'Drug Safety Evaluation'

Table of Contents

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    Book Overview
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    Chapter 1 Developing Combination Drugs in Preclinical Studies
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    Chapter 2 Preclinical Evaluation of Juvenile Toxicity
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    Chapter 3 Necropsy and Sampling Procedures in Rodents
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    Chapter 4 Histopathology Procedures: From Tissue Sampling to Histopathological Evaluation
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    Chapter 5 Principles and methods of immunohistochemistry.
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    Chapter 6 Tissue Microarrays and Digital Image Analysis
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    Chapter 7 Micronucleus Assay and Labeling of Centromeres with FISH Technique
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    Chapter 8 The Use of Bacterial Repair Endonucleases in the Comet Assay
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    Chapter 9 Manual Whole-Cell Patch-Clamping of the HERG Cardiac K + Channel
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    Chapter 10 Generation and Analysis of Transcriptomics Data
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    Chapter 11 Protocols of Two-Dimensional Difference Gel Electrophoresis to Investigate Mechanisms of Toxicity
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    Chapter 12 Protocols and Applications of Cellular Metabolomics in Safety Studies Using Precision-Cut Tissue Slices and Carbon 13 NMR
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    Chapter 13 Statistical analysis of quantitative RT-PCR results.
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    Chapter 14 Evaluation of Mitochondrial Respiration in Cultured Rat Hepatocytes
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    Chapter 15 FETAX Assay for Evaluation of Developmental Toxicity
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    Chapter 16 Evaluation of Embryotoxicity Using the Zebrafish Model
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    Chapter 17 Protocols of In Vitro Protein Covalent Binding Studies in Liver
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    Chapter 18 Utilization of MALDI-TOF to Determine Chemical-Protein Adduct Formation In Vitro
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    Chapter 19 Utilization of LC-MS/MS Analyses to Identify Site-Specific Chemical Protein Adducts In Vitro
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    Chapter 20 One-Dimensional Western Blotting Coupled to LC-MS/MS Analysis to Identify Chemical-Adducted Proteins in Rat Urine
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    Chapter 21 Identification of Chemical-Adducted Proteins in Urine by Multi-dimensional Protein Identification Technology (LC/LC–MS/MS)
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    Chapter 22 Optimization of SELDI for Biomarker Detection in Plasma
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    Chapter 23 Drug Safety Evaluation
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    Chapter 24 NMR and MS methods for metabonomics.
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    Chapter 25 Drug Safety Evaluation
Attention for Chapter 6: Tissue Microarrays and Digital Image Analysis
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Citations

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Chapter title
Tissue Microarrays and Digital Image Analysis
Chapter number 6
Book title
Drug Safety Evaluation
Published in
Methods in molecular biology, January 2011
DOI 10.1007/978-1-60761-849-2_6
Pubmed ID
Book ISBNs
978-1-60327-186-8, 978-1-60761-849-2
Authors

Denise Ryan, Laoighse Mulrane, Elton Rexhepaj, William M. Gallagher, Ryan, Denise, Mulrane, Laoighse, Rexhepaj, Elton, Gallagher, William M.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 6 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Japan 1 17%
Unknown 5 83%

Demographic breakdown

Readers by professional status Count As %
Professor 2 33%
Student > Bachelor 1 17%
Student > Ph. D. Student 1 17%
Researcher 1 17%
Student > Postgraduate 1 17%
Other 0 0%
Readers by discipline Count As %
Medicine and Dentistry 4 67%
Psychology 1 17%
Computer Science 1 17%