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Human Embryonic Stem Cells Differentiated to Lung Lineage-Specific Cells Ameliorate Pulmonary Fibrosis in a Xenograft Transplant Mouse Model

Overview of attention for article published in PLOS ONE, March 2012
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • Good Attention Score compared to outputs of the same age (76th percentile)
  • Good Attention Score compared to outputs of the same age and source (72nd percentile)

Mentioned by

twitter
2 X users
wikipedia
1 Wikipedia page
f1000
1 research highlight platform

Citations

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88 Dimensions

Readers on

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88 Mendeley
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1 CiteULike
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Title
Human Embryonic Stem Cells Differentiated to Lung Lineage-Specific Cells Ameliorate Pulmonary Fibrosis in a Xenograft Transplant Mouse Model
Published in
PLOS ONE, March 2012
DOI 10.1371/journal.pone.0033165
Pubmed ID
Authors

Ena Ray Banerjee, Michael A. Laflamme, Thalia Papayannopoulou, Michael Kahn, Charles E. Murry, William R. Henderson

Abstract

Our aim was to differentiate human (h) embryonic stem (ES) cells into lung epithelial lineage-specific cells [i.e., alveolar epithelial type I (AEI) and type II (AEII) cells and Clara cells] as the first step in the development of cell-based strategies to repair lung injury in the bleomycin mouse model of idiopathic pulmonary fibrosis (IPF). A heterogeneous population of non-ciliated lung lineage-specific cells was derived by a novel method of embryoid body (EB) differentiation. This differentiated human cell population was used to modulate the profibrotic phenotype in transplanted animals.

X Demographics

X Demographics

The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 88 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Japan 1 1%
Unknown 87 99%

Demographic breakdown

Readers by professional status Count As %
Researcher 17 19%
Student > Ph. D. Student 13 15%
Student > Bachelor 10 11%
Student > Postgraduate 6 7%
Student > Doctoral Student 5 6%
Other 12 14%
Unknown 25 28%
Readers by discipline Count As %
Agricultural and Biological Sciences 23 26%
Medicine and Dentistry 15 17%
Biochemistry, Genetics and Molecular Biology 11 13%
Engineering 4 5%
Unspecified 2 2%
Other 7 8%
Unknown 26 30%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 6. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 07 January 2021.
All research outputs
#5,614,370
of 22,663,969 outputs
Outputs from PLOS ONE
#67,995
of 193,506 outputs
Outputs of similar age
#37,828
of 160,394 outputs
Outputs of similar age from PLOS ONE
#1,026
of 3,700 outputs
Altmetric has tracked 22,663,969 research outputs across all sources so far. Compared to these this one has done well and is in the 75th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 193,506 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 15.0. This one has gotten more attention than average, scoring higher than 64% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 160,394 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 76% of its contemporaries.
We're also able to compare this research output to 3,700 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 72% of its contemporaries.