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The association between phthalates and metabolic syndrome: the National Health and Nutrition Examination Survey 2001–2010

Overview of attention for article published in Environmental Health, April 2016
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (91st percentile)
  • Good Attention Score compared to outputs of the same age and source (71st percentile)

Mentioned by

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2 news outlets
policy
1 policy source
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5 X users
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1 YouTube creator

Citations

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96 Dimensions

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106 Mendeley
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Title
The association between phthalates and metabolic syndrome: the National Health and Nutrition Examination Survey 2001–2010
Published in
Environmental Health, April 2016
DOI 10.1186/s12940-016-0136-x
Pubmed ID
Authors

Tamarra M. James-Todd, Tianyi Huang, Ellen W. Seely, Aditi R. Saxena

Abstract

Higher exposure to certain phthalates is associated with a diabetes and insulin resistance, with sex differences seen. Yet, little is known about the association between phthalates and metabolic syndrome (MetS), particularly with consideration for differences by sex and menopausal status. We analyzed data from 2719 participants in the National Health and Nutrition Examination Survey (NHANES) 2001-2010 aged 20-80 years. Five urinary phthalate metabolites (MEP, MnBP, MiBP, MBzP, and MCPP) and DEHP metabolites were analyzed by the Centers for Disease Control and Prevention and were evaluated as population-specific quartiles. MetS was defined by National Cholesterol Education Program's Adult Treatment Panel III report criteria. Prevalence odds ratios (POR) and 95 % confidence intervals (CI) were calculated using multivariable logistic regression, adjusting for potential confounders and stratifying by sex and menopausal status. Participants with MetS (32 % of the study population) had higher concentrations for all urinary phthalate metabolites. After full adjustment, higher DEHP metabolite concentrations were associated with an increased odds of MetS in men, but not women (adj. POR for men Q4 versus Q1: 2.20; 95 % CI: 1.32, 3.68 and adj. POR for women Q4 versus Q1: 1.50; 95 % CI: 0.89, 2.52). When evaluating by menopausal status, pre-menopausal women with higher concentrations of MBzP had close to a 4-fold increased odds of MetS compared to pre-menopausal women with the lowest concentrations of MBzP (adj POR: Q4 versus Q1: 3.88; 95 % CI: 1.59, 9.49). Higher concentrations of certain phthalate metabolites were associated with an increased odds of MetS. Higher DEHP metabolite concentrations were associated with an increased odds of MetS for men. In women, the strongest association was between higher concentrations of MBzP and MetS, but only among pre-menopausal women.

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X Demographics

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 106 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 106 100%

Demographic breakdown

Readers by professional status Count As %
Student > Master 13 12%
Researcher 12 11%
Student > Bachelor 11 10%
Student > Ph. D. Student 11 10%
Student > Doctoral Student 7 7%
Other 14 13%
Unknown 38 36%
Readers by discipline Count As %
Medicine and Dentistry 14 13%
Nursing and Health Professions 13 12%
Biochemistry, Genetics and Molecular Biology 10 9%
Agricultural and Biological Sciences 6 6%
Pharmacology, Toxicology and Pharmaceutical Science 5 5%
Other 18 17%
Unknown 40 38%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 24. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 01 January 2022.
All research outputs
#1,481,863
of 24,393,299 outputs
Outputs from Environmental Health
#317
of 1,559 outputs
Outputs of similar age
#25,284
of 305,415 outputs
Outputs of similar age from Environmental Health
#11
of 35 outputs
Altmetric has tracked 24,393,299 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 93rd percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 1,559 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 36.9. This one has done well, scoring higher than 79% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 305,415 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 91% of its contemporaries.
We're also able to compare this research output to 35 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 71% of its contemporaries.