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Lactobacillus helveticus Lafti L10 Supplementation Modulates Mucosal and Humoral Immunity in Elite Athletes: A Randomized, Double-Blind, Placebo-Controlled Trial

Overview of attention for article published in Journal of Strength & Conditioning Research, January 2017
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (90th percentile)
  • Good Attention Score compared to outputs of the same age and source (67th percentile)

Mentioned by

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28 tweeters
facebook
5 Facebook pages
video
1 video uploader

Citations

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17 Dimensions

Readers on

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68 Mendeley
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Title
Lactobacillus helveticus Lafti L10 Supplementation Modulates Mucosal and Humoral Immunity in Elite Athletes: A Randomized, Double-Blind, Placebo-Controlled Trial
Published in
Journal of Strength & Conditioning Research, January 2017
DOI 10.1519/jsc.0000000000001456
Pubmed ID
Authors

Danica M. Michalickova, Marija M. Kostic-Vucicevic, Milica Dj. Vukasinovic-Vesic, Tamara B. Stojmenovic, Nenad V. Dikic, Marija S. Andjelkovic, Brizita I. Djordjevic, Bojana P. Tanaskovic, Rajna D. Minic

Abstract

In order to test the influence of probiotic supplementation on humoral immune response a double-blind placebo-controlled trial was conducted. Thirty athletes (24 males and 6 females, females: VO2max 38.2 ± 4.9 ml/kg/min, age 23.2 ± 1.4 years; males: VO2max 57.5 ± 9.2 ml/kg/min, age 24.0 ± 2.4 years, mean ± SD) were randomized either to the probiotic group (L. helveticus Lafti® L10, 2 x 10 CFU), or to the placebo group. Serum and saliva samples were collected at the baseline and after 14 weeks. Total and specific anti-bacterial antibody levels of IgM, IgG and IgA classes were determined towards different bacteria in the serum, while in saliva total and specific anti-bacterial IgA levels were examined. Total IgM was elevated in both probiotic (18%, 15 to 20%; mean, 90% confidence interval; p=0.02) and placebo group (35%, 22 to 47%; p=0.02), without observed differences in changes between the groups. No significant changes in IgM levels specific for tested bacteria were found. Total IgG level was constant in both groups. A significant (16%, -2.8 to 35%, p=0.04) reduction of anti - Enterococcus faecalis IgG was noted in the placebo group, in comparation to the probiotic group. There was a substantial decrease in total IgA level in the placebo group, when measured either in serum (15%, 12 to 18%, p=0.04) or in saliva (35%, -1.4 to 53%, p=0.03). The significantly reduced levels of serum anti-LAB IgA antibodies in the placebo group compared to the probiotic group were detected for L. rhamnosus LA68 for (24%, 5.8 to 42%, p=0.02) and for L. rhamnosus LB64 for (15%, 2.7 to 27%, p=0.02). Probiotic administration could have beneficial effects on systemic humoral and mucosal immune responses.

Twitter Demographics

The data shown below were collected from the profiles of 28 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 68 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Poland 1 1%
Unknown 67 99%

Demographic breakdown

Readers by professional status Count As %
Student > Master 12 18%
Student > Bachelor 10 15%
Researcher 8 12%
Student > Doctoral Student 5 7%
Other 4 6%
Other 11 16%
Unknown 18 26%
Readers by discipline Count As %
Medicine and Dentistry 12 18%
Nursing and Health Professions 10 15%
Sports and Recreations 6 9%
Biochemistry, Genetics and Molecular Biology 5 7%
Agricultural and Biological Sciences 3 4%
Other 9 13%
Unknown 23 34%

Attention Score in Context

This research output has an Altmetric Attention Score of 20. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 29 February 2020.
All research outputs
#1,523,541
of 21,797,833 outputs
Outputs from Journal of Strength & Conditioning Research
#1,385
of 6,260 outputs
Outputs of similar age
#26,930
of 279,551 outputs
Outputs of similar age from Journal of Strength & Conditioning Research
#35
of 106 outputs
Altmetric has tracked 21,797,833 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 93rd percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 6,260 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 17.8. This one has done well, scoring higher than 77% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 279,551 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 90% of its contemporaries.
We're also able to compare this research output to 106 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 67% of its contemporaries.