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A benchmark for RNA-seq quantification pipelines

Overview of attention for article published in Genome Biology, April 2016
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About this Attention Score

  • In the top 5% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (98th percentile)
  • High Attention Score compared to outputs of the same age and source (96th percentile)

Mentioned by

news
1 news outlet
blogs
2 blogs
twitter
179 X users
facebook
3 Facebook pages
reddit
1 Redditor

Citations

dimensions_citation
169 Dimensions

Readers on

mendeley
736 Mendeley
citeulike
12 CiteULike
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Title
A benchmark for RNA-seq quantification pipelines
Published in
Genome Biology, April 2016
DOI 10.1186/s13059-016-0940-1
Pubmed ID
Authors

Mingxiang Teng, Michael I. Love, Carrie A. Davis, Sarah Djebali, Alexander Dobin, Brenton R. Graveley, Sheng Li, Christopher E. Mason, Sara Olson, Dmitri Pervouchine, Cricket A. Sloan, Xintao Wei, Lijun Zhan, Rafael A. Irizarry

Abstract

Obtaining RNA-seq measurements involves a complex data analytical process with a large number of competing algorithms as options. There is much debate about which of these methods provides the best approach. Unfortunately, it is currently difficult to evaluate their performance due in part to a lack of sensitive assessment metrics. We present a series of statistical summaries and plots to evaluate the performance in terms of specificity and sensitivity, available as a R/Bioconductor package ( http://bioconductor.org/packages/rnaseqcomp ). Using two independent datasets, we assessed seven competing pipelines. Performance was generally poor, with two methods clearly underperforming and RSEM slightly outperforming the rest.

X Demographics

X Demographics

The data shown below were collected from the profiles of 179 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 736 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 15 2%
United Kingdom 9 1%
Germany 4 <1%
Italy 3 <1%
Mexico 3 <1%
Sweden 3 <1%
Denmark 2 <1%
France 2 <1%
Canada 2 <1%
Other 14 2%
Unknown 679 92%

Demographic breakdown

Readers by professional status Count As %
Researcher 208 28%
Student > Ph. D. Student 174 24%
Student > Master 84 11%
Student > Bachelor 49 7%
Student > Doctoral Student 37 5%
Other 111 15%
Unknown 73 10%
Readers by discipline Count As %
Agricultural and Biological Sciences 255 35%
Biochemistry, Genetics and Molecular Biology 235 32%
Computer Science 47 6%
Medicine and Dentistry 20 3%
Engineering 17 2%
Other 67 9%
Unknown 95 13%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 122. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 03 August 2022.
All research outputs
#342,793
of 25,374,917 outputs
Outputs from Genome Biology
#153
of 4,467 outputs
Outputs of similar age
#6,239
of 313,371 outputs
Outputs of similar age from Genome Biology
#3
of 76 outputs
Altmetric has tracked 25,374,917 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 98th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 4,467 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 27.6. This one has done particularly well, scoring higher than 96% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 313,371 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 98% of its contemporaries.
We're also able to compare this research output to 76 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 96% of its contemporaries.