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Recombinant Human Endostatin Normalizes Tumor Vasculature and Enhances Radiation Response in Xenografted Human Nasopharyngeal Carcinoma Models

Overview of attention for article published in PLOS ONE, April 2012
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About this Attention Score

  • Good Attention Score compared to outputs of the same age (67th percentile)
  • Above-average Attention Score compared to outputs of the same age and source (61st percentile)

Mentioned by

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1 X user
patent
1 patent

Citations

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69 Dimensions

Readers on

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36 Mendeley
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Title
Recombinant Human Endostatin Normalizes Tumor Vasculature and Enhances Radiation Response in Xenografted Human Nasopharyngeal Carcinoma Models
Published in
PLOS ONE, April 2012
DOI 10.1371/journal.pone.0034646
Pubmed ID
Authors

Fang Peng, Zumin Xu, Jin Wang, Yuanyuan Chen, Qiang Li, Yufang Zuo, Jing Chen, Xiao Hu, Qichao Zhou, Yan Wang, Honglian Ma, Yong Bao, Ming Chen

Abstract

Hypoxic tumor cells can reduce the efficacy of radiation. Antiangiogenic therapy may transiently "normalize" the tumor vasculature to make it more efficient for oxygen delivery. The aim of this study is to investigate whether the recombinant human endostatin (endostar) can create a "vascular normalization window" to alleviate hypoxia and enhance the inhibitory effects of radiation therapy in human nasopharyngeal carcinoma (NPC) in mice.

X Demographics

X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 36 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Canada 1 3%
Unknown 35 97%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 11 31%
Researcher 5 14%
Student > Bachelor 3 8%
Student > Doctoral Student 2 6%
Other 2 6%
Other 8 22%
Unknown 5 14%
Readers by discipline Count As %
Medicine and Dentistry 12 33%
Agricultural and Biological Sciences 4 11%
Biochemistry, Genetics and Molecular Biology 3 8%
Nursing and Health Professions 2 6%
Chemistry 2 6%
Other 6 17%
Unknown 7 19%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 4. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 08 June 2017.
All research outputs
#7,170,382
of 22,664,267 outputs
Outputs from PLOS ONE
#84,728
of 193,506 outputs
Outputs of similar age
#50,672
of 161,201 outputs
Outputs of similar age from PLOS ONE
#1,374
of 3,654 outputs
Altmetric has tracked 22,664,267 research outputs across all sources so far. This one has received more attention than most of these and is in the 67th percentile.
So far Altmetric has tracked 193,506 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 15.0. This one has gotten more attention than average, scoring higher than 55% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 161,201 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 67% of its contemporaries.
We're also able to compare this research output to 3,654 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 61% of its contemporaries.