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Development of B Cells and Erythrocytes Is Specifically Impaired by the Drug Celastrol in Mice

Overview of attention for article published in PLOS ONE, April 2012
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2 X users

Citations

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28 Dimensions

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19 Mendeley
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Title
Development of B Cells and Erythrocytes Is Specifically Impaired by the Drug Celastrol in Mice
Published in
PLOS ONE, April 2012
DOI 10.1371/journal.pone.0035733
Pubmed ID
Authors

Sophie Kusy, Eliver E. B. Ghosn, Leonore A. Herzenberg, Christopher H. Contag

Abstract

Celastrol, an active compound extracted from the root of the Chinese medicine "Thunder of God Vine" (Tripterygium wilfordii), exhibits anticancer, antioxidant and anti-inflammatory activities, and interest in the therapeutic potential of celastrol is increasing. However, described side effects following treatment are significant and require investigation prior to initiating clinical trials. Here, we investigated the effects of celastrol on the adult murine hematopoietic system.

X Demographics

X Demographics

The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 19 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Spain 1 5%
United States 1 5%
Unknown 17 89%

Demographic breakdown

Readers by professional status Count As %
Researcher 8 42%
Student > Ph. D. Student 3 16%
Student > Doctoral Student 2 11%
Student > Master 2 11%
Lecturer > Senior Lecturer 1 5%
Other 0 0%
Unknown 3 16%
Readers by discipline Count As %
Agricultural and Biological Sciences 7 37%
Biochemistry, Genetics and Molecular Biology 3 16%
Medicine and Dentistry 3 16%
Chemistry 2 11%
Unknown 4 21%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 16 May 2012.
All research outputs
#14,725,727
of 22,664,644 outputs
Outputs from PLOS ONE
#122,859
of 193,509 outputs
Outputs of similar age
#101,062
of 163,178 outputs
Outputs of similar age from PLOS ONE
#2,274
of 3,747 outputs
Altmetric has tracked 22,664,644 research outputs across all sources so far. This one is in the 32nd percentile – i.e., 32% of other outputs scored the same or lower than it.
So far Altmetric has tracked 193,509 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 15.0. This one is in the 33rd percentile – i.e., 33% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 163,178 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 36th percentile – i.e., 36% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 3,747 others from the same source and published within six weeks on either side of this one. This one is in the 35th percentile – i.e., 35% of its contemporaries scored the same or lower than it.