Title |
Mechanisms used by inulin-type fructans to improve the lipid profile.
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Published in |
Nutrición Hospitalaria, January 2014
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DOI | 10.3305/nh.2015.31.2.7706 |
Pubmed ID | |
Authors |
Sandra Aparecida dos Reis, Lisiane Lopes da Conceição, Damiana Diniz Rosa, Manoela Maciel dos Santos Dias, Maria do Carmo Gouveia Peluzio |
Abstract |
The consumption of prebiotics has been associated with improvement in the lipid profile. Thus, this review aims to describe the main mechanisms by which inulin-type fructans improve the lipid profile and thereby reduce the cardiovascular risk. Inulin-type fructans have been demonstrated to improve the lipid profile through a number of mechanisms. These mechanisms include: decrease in gene expression of hepatic enzymes responsible for de novo synthesis of lipids; increase of muscle lipoprotein lipase enzyme activity, enhancing the production of short-chain fatty acids; altered production of polyamines which increases the production of satiogenic peptide; altered blood glucose and insulinemia; increase of fecal excretion of bile salts and cholesterol and increase of the Bifidobacterium population. The consumption of inulin-type fructans enhances lipid profile. Generally, the mechanisms vary according to the physiologic state of the individual and the type of diet to which the inulin-type fructans are added. Thus, inulin may be used for the prevention and/or treatment of cardiovascular diseases. |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 44 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Bachelor | 3 | 7% |
Student > Master | 2 | 5% |
Student > Ph. D. Student | 2 | 5% |
Professor | 1 | 2% |
Researcher | 1 | 2% |
Other | 1 | 2% |
Unknown | 34 | 77% |
Readers by discipline | Count | As % |
---|---|---|
Chemistry | 2 | 5% |
Pharmacology, Toxicology and Pharmaceutical Science | 1 | 2% |
Biochemistry, Genetics and Molecular Biology | 1 | 2% |
Chemical Engineering | 1 | 2% |
Computer Science | 1 | 2% |
Other | 3 | 7% |
Unknown | 35 | 80% |