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A Common Susceptibility Factor of Both Autism and Epilepsy: Functional Deficiency of GABAA Receptors

Overview of attention for article published in Journal of Autism and Developmental Disorders, May 2012
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (86th percentile)
  • Good Attention Score compared to outputs of the same age and source (66th percentile)

Mentioned by

blogs
1 blog
twitter
2 X users
facebook
1 Facebook page

Citations

dimensions_citation
47 Dimensions

Readers on

mendeley
120 Mendeley
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Title
A Common Susceptibility Factor of Both Autism and Epilepsy: Functional Deficiency of GABAA Receptors
Published in
Journal of Autism and Developmental Disorders, May 2012
DOI 10.1007/s10803-012-1543-7
Pubmed ID
Authors

Jing-Qiong Kang, Gregory Barnes

Abstract

Autism and epilepsy are common childhood neurological disorders with a great heterogeneity of clinical phenotypes as well as risk factors. There is a high co-morbidity of autism and epilepsy. The neuropathology of autism and epilepsy has similar histology implicating the processes of neurogenesis, neural migration, programmed cell death, and neurite outgrowth. Genetic advances have identified multiple molecules that participate in neural development, brain network connectivity, and synaptic function which are involved in the pathogenesis of autism and epilepsy. Mutations in GABA(A) receptor subunit have been frequently associated with epilepsy, autism, and other neuropsychiatric disorders. In this paper, we address the hypothesis that functional deficiency of GABAergic signaling is a potential common molecular mechanism underpinning the co-morbidity of autism and epilepsy.

X Demographics

X Demographics

The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 120 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 1 <1%
Unknown 119 99%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 26 22%
Researcher 16 13%
Student > Master 13 11%
Student > Doctoral Student 11 9%
Student > Bachelor 11 9%
Other 24 20%
Unknown 19 16%
Readers by discipline Count As %
Neuroscience 22 18%
Psychology 19 16%
Agricultural and Biological Sciences 18 15%
Medicine and Dentistry 18 15%
Biochemistry, Genetics and Molecular Biology 9 8%
Other 16 13%
Unknown 18 15%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 10. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 19 July 2013.
All research outputs
#3,816,209
of 25,654,806 outputs
Outputs from Journal of Autism and Developmental Disorders
#1,580
of 5,484 outputs
Outputs of similar age
#24,145
of 176,814 outputs
Outputs of similar age from Journal of Autism and Developmental Disorders
#19
of 56 outputs
Altmetric has tracked 25,654,806 research outputs across all sources so far. Compared to these this one has done well and is in the 85th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 5,484 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 13.4. This one has gotten more attention than average, scoring higher than 71% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 176,814 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 86% of its contemporaries.
We're also able to compare this research output to 56 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 66% of its contemporaries.