The concept of multiple gene mutations acting together in cancer is not new. But it has been hard to study whether the same happens in large deletions/monosomies. Work from Scott Lowe's lab shows a cluster of cooperating TSGs on Chr 8p https://t.co/yzIbqkH
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A cluster of cooperating tumor-suppressor gene candidates in chromosomal deletions. http://t.co/FlA12Ymi #in
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一つのTumor suppressor geneの欠損だけでない。RT PNAS study suggests modifications to "two-hit" hypothesis of #cancer: http://t.co/h7C5MLrX;
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PNAS study suggests modifications to "two-hit" hypothesis of #cancer: http://t.co/XZQ50nod; http://t.co/pTAnje5y