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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Vitamin C in human health and disease is still a mystery? An overview
|
|---|---|
| Published in |
Nutrition Journal, August 2003
|
| DOI | 10.1186/1475-2891-2-7 |
| Pubmed ID | |
| Authors |
K Akhilender Naidu |
| Abstract |
Ascorbic acid is one of the important water soluble vitamins. It is essential for collagen, carnitine and neurotransmitters biosynthesis. Most plants and animals synthesize ascorbic acid for their own requirement. However, apes and humans can not synthesize ascorbic acid due to lack of an enzyme gulonolactone oxidase. Hence, ascorbic acid has to be supplemented mainly through fruits, vegetables and tablets. The current US recommended daily allowance (RDA) for ascorbic acid ranges between 100-120 mg/per day for adults. Many health benefits have been attributed to ascorbic acid such as antioxidant, anti-atherogenic, anti-carcinogenic, immunomodulator and prevents cold etc. However, lately the health benefits of ascorbic acid has been the subject of debate and controversies viz., Danger of mega doses of ascorbic acid? Does ascorbic acid act as a antioxidant or pro-oxidant? Does ascorbic acid cause cancer or may interfere with cancer therapy? However, the Panel on dietary antioxidants and related compounds stated that the in vivo data do not clearly show a relationship between excess ascorbic acid intake and kidney stone formation, pro-oxidant effects, excess iron absorption. A number of clinical and epidemiological studies on anti-carcinogenic effects of ascorbic acid in humans did not show any conclusive beneficial effects on various types of cancer except gastric cancer. Recently, a few derivatives of ascorbic acid were tested on cancer cells, among them ascorbic acid esters showed promising anticancer activity compared to ascorbic acid. Ascorbyl stearate was found to inhibit proliferation of human cancer cells by interfering with cell cycle progression, induced apoptosis by modulation of signal transduction pathways. However, more mechanistic and human in vivo studies are needed to understand and elucidate the molecular mechanism underlying the anti-carcinogenic property of ascorbic acid. Thus, though ascorbic acid was discovered in 17th century, the exact role of this vitamin/nutraceutical in human biology and health is still a mystery in view of many beneficial claims and controversies. |
X Demographics
The data shown below were collected from the profiles of 17 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 4 | 24% |
| United Kingdom | 3 | 18% |
| Hungary | 1 | 6% |
| Spain | 1 | 6% |
| Indonesia | 1 | 6% |
| Unknown | 7 | 41% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 13 | 76% |
| Practitioners (doctors, other healthcare professionals) | 2 | 12% |
| Scientists | 2 | 12% |
Mendeley readers
The data shown below were compiled from readership statistics for 539 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 2 | <1% |
| Portugal | 1 | <1% |
| France | 1 | <1% |
| Austria | 1 | <1% |
| Australia | 1 | <1% |
| Bangladesh | 1 | <1% |
| New Zealand | 1 | <1% |
| Brazil | 1 | <1% |
| Spain | 1 | <1% |
| Other | 1 | <1% |
| Unknown | 528 | 98% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Bachelor | 106 | 20% |
| Student > Master | 66 | 12% |
| Researcher | 42 | 8% |
| Student > Ph. D. Student | 41 | 8% |
| Student > Postgraduate | 25 | 5% |
| Other | 70 | 13% |
| Unknown | 189 | 35% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 89 | 17% |
| Medicine and Dentistry | 54 | 10% |
| Biochemistry, Genetics and Molecular Biology | 52 | 10% |
| Pharmacology, Toxicology and Pharmaceutical Science | 35 | 6% |
| Chemistry | 31 | 6% |
| Other | 67 | 12% |
| Unknown | 211 | 39% |
Attention Score in Context
This research output has an Altmetric Attention Score of 41. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 06 April 2024.
All research outputs
#1,010,902
of 25,367,237 outputs
Outputs from Nutrition Journal
#286
of 1,517 outputs
Outputs of similar age
#875
of 53,909 outputs
Outputs of similar age from Nutrition Journal
#1
of 2 outputs
Altmetric has tracked 25,367,237 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 96th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 1,517 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 39.6. This one has done well, scoring higher than 81% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 53,909 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 98% of its contemporaries.
We're also able to compare this research output to 2 others from the same source and published within six weeks on either side of this one. This one has scored higher than all of them