Title |
Clinical correlates of chronic cerebrospinal venous insufficiency in multiple sclerosis
|
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Published in |
BMC Neurology, May 2012
|
DOI | 10.1186/1471-2377-12-26 |
Pubmed ID | |
Authors |
Bianca Weinstock-Guttman, Murali Ramanathan, Karen Marr, David Hojnacki, Ralph HB Benedict, Charity Morgan, Eluen Ann Yeh, Ellen Carl, Cheryl Kennedy, Justine Reuther, Christina Brooks, Kristin Hunt, Makki Elfadil, Michelle Andrews, Robert Zivadinov |
Abstract |
Chronic cerebrospinal venous insufficiency (CCSVI) is a vascular condition characterized by anomalies of the primary veins outside the skull that has been reported to be associated with MS. In the blinded Combined Transcranial (TCD) and Extracranial Venous Doppler Evaluation (CTEVD) study, we found that prevalence of CCSVI was significantly higher in multiple sclerosis (MS) vs. healthy controls (HC) (56.1% vs. 22.7%, p < 0.001).The objective was to evaluate the clinical correlates of venous anomalies indicative of CCSVI in patients with MS. |
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