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Comparison of low and high dose ionising radiation using topological analysis of gene coexpression networks

Overview of attention for article published in BMC Genomics, May 2012
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  • In the top 25% of all research outputs scored by Altmetric
  • Good Attention Score compared to outputs of the same age (77th percentile)
  • High Attention Score compared to outputs of the same age and source (83rd percentile)

Mentioned by

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8 X users

Citations

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21 Dimensions

Readers on

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32 Mendeley
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1 CiteULike
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Title
Comparison of low and high dose ionising radiation using topological analysis of gene coexpression networks
Published in
BMC Genomics, May 2012
DOI 10.1186/1471-2164-13-190
Pubmed ID
Authors

Monika Ray, Reem Yunis, Xiucui Chen, David M Rocke

Abstract

The growing use of imaging procedures in medicine has raised concerns about exposure to low-dose ionising radiation (LDIR). While the disastrous effects of high dose ionising radiation (HDIR) is well documented, the detrimental effects of LDIR is not well understood and has been a topic of much debate. Since little is known about the effects of LDIR, various kinds of wet-lab and computational analyses are required to advance knowledge in this domain. In this paper we carry out an "upside-down pyramid" form of systems biology analysis of microarray data. We characterised the global genomic response following 10 cGy (low dose) and 100 cGy (high dose) doses of X-ray ionising radiation at four time points by analysing the topology of gene coexpression networks. This study includes a rich experimental design and state-of-the-art computational systems biology methods of analysis to study the differences in the transcriptional response of skin cells exposed to low and high doses of radiation.

X Demographics

X Demographics

The data shown below were collected from the profiles of 8 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 32 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Netherlands 1 3%
France 1 3%
Unknown 30 94%

Demographic breakdown

Readers by professional status Count As %
Researcher 7 22%
Student > Master 4 13%
Student > Ph. D. Student 3 9%
Student > Bachelor 2 6%
Student > Doctoral Student 2 6%
Other 5 16%
Unknown 9 28%
Readers by discipline Count As %
Agricultural and Biological Sciences 9 28%
Biochemistry, Genetics and Molecular Biology 5 16%
Mathematics 2 6%
Computer Science 2 6%
Environmental Science 1 3%
Other 5 16%
Unknown 8 25%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 6. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 20 May 2012.
All research outputs
#5,564,527
of 23,340,595 outputs
Outputs from BMC Genomics
#2,187
of 10,745 outputs
Outputs of similar age
#37,974
of 165,812 outputs
Outputs of similar age from BMC Genomics
#14
of 87 outputs
Altmetric has tracked 23,340,595 research outputs across all sources so far. Compared to these this one has done well and is in the 76th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 10,745 research outputs from this source. They receive a mean Attention Score of 4.7. This one has done well, scoring higher than 79% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 165,812 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 77% of its contemporaries.
We're also able to compare this research output to 87 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 83% of its contemporaries.