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Impact of chemotherapy on cancer-related fatigue and cytokines in 1312 patients

Overview of attention for article published in Current Opinion in Supportive and Palliative Care, June 2016
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Title
Impact of chemotherapy on cancer-related fatigue and cytokines in 1312 patients
Published in
Current Opinion in Supportive and Palliative Care, June 2016
DOI 10.1097/spc.0000000000000205
Pubmed ID
Authors

Tewodros Eyob, Terence Ng, Raymond Chan, Alexandre Chan

Abstract

Cancer-related fatigue (CRF) is the most common psychosomatic distress experienced by cancer patients before, during and after chemotherapy. Its impact on functional status and Health Related Quality of Life is a great concern among patients, healthcare professionals and researchers. The primary objective of this systematic review is to determine whether the different chemotherapies affect the association of CRF with individual pro- and anti-inflammatory cytokines. The PRISMA statement guideline has been followed to systematically search and screen article from PubMed and Embase. This review has examined 14 studies which included a total of 1312 patients. These studies assayed 20 different kinds of cytokines. The cytokines interleukin-6, interleukin-1RA, TGF-β and sTNF-R2 were associated with CRF in patients receiving anthracycline-based chemotherapy. However, only interleukin-13 was identified in the taxane-based chemotherapy. Similarly, different sets of cytokines were linked with CRF in patients with chemotherapy regimens containing platinum, cyclophosphamides, topotecan or bleomycin. This review has identified that cytokines are differentially linked with CRF according to the various types of chemotherapy regimens.

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The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 39 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Portugal 1 3%
Unknown 38 97%

Demographic breakdown

Readers by professional status Count As %
Professor 4 10%
Student > Master 4 10%
Student > Ph. D. Student 4 10%
Student > Doctoral Student 3 8%
Other 3 8%
Other 7 18%
Unknown 14 36%
Readers by discipline Count As %
Nursing and Health Professions 8 21%
Medicine and Dentistry 7 18%
Pharmacology, Toxicology and Pharmaceutical Science 2 5%
Biochemistry, Genetics and Molecular Biology 1 3%
Unspecified 1 3%
Other 4 10%
Unknown 16 41%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 17 May 2016.
All research outputs
#20,656,161
of 25,373,627 outputs
Outputs from Current Opinion in Supportive and Palliative Care
#453
of 677 outputs
Outputs of similar age
#269,917
of 353,659 outputs
Outputs of similar age from Current Opinion in Supportive and Palliative Care
#7
of 13 outputs
Altmetric has tracked 25,373,627 research outputs across all sources so far. This one is in the 10th percentile – i.e., 10% of other outputs scored the same or lower than it.
So far Altmetric has tracked 677 research outputs from this source. They receive a mean Attention Score of 4.4. This one is in the 4th percentile – i.e., 4% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 353,659 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 12th percentile – i.e., 12% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 13 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.