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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Organ-on-a-chip: recent breakthroughs and future prospects
|
|---|---|
| Published in |
BioMedical Engineering OnLine, February 2020
|
| DOI | 10.1186/s12938-020-0752-0 |
| Pubmed ID | |
| Authors |
Qirui Wu, Jinfeng Liu, Xiaohong Wang, Lingyan Feng, Jinbo Wu, Xiaoli Zhu, Weijia Wen, Xiuqing Gong |
| Abstract |
The organ-on-a-chip (OOAC) is in the list of top 10 emerging technologies and refers to a physiological organ biomimetic system built on a microfluidic chip. Through a combination of cell biology, engineering, and biomaterial technology, the microenvironment of the chip simulates that of the organ in terms of tissue interfaces and mechanical stimulation. This reflects the structural and functional characteristics of human tissue and can predict response to an array of stimuli including drug responses and environmental effects. OOAC has broad applications in precision medicine and biological defense strategies. Here, we introduce the concepts of OOAC and review its application to the construction of physiological models, drug development, and toxicology from the perspective of different organs. We further discuss existing challenges and provide future perspectives for its application. |
X Demographics
The data shown below were collected from the profiles of 10 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Canada | 4 | 40% |
| United States | 2 | 20% |
| United Kingdom | 1 | 10% |
| Unknown | 3 | 30% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 9 | 90% |
| Scientists | 1 | 10% |
Mendeley readers
The data shown below were compiled from readership statistics for 1,286 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 1286 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Bachelor | 197 | 15% |
| Student > Ph. D. Student | 172 | 13% |
| Student > Master | 145 | 11% |
| Researcher | 97 | 8% |
| Student > Doctoral Student | 38 | 3% |
| Other | 112 | 9% |
| Unknown | 525 | 41% |
| Readers by discipline | Count | As % |
|---|---|---|
| Biochemistry, Genetics and Molecular Biology | 199 | 15% |
| Engineering | 197 | 15% |
| Agricultural and Biological Sciences | 47 | 4% |
| Medicine and Dentistry | 45 | 3% |
| Pharmacology, Toxicology and Pharmaceutical Science | 40 | 3% |
| Other | 191 | 15% |
| Unknown | 567 | 44% |
Attention Score in Context
This research output has an Altmetric Attention Score of 43. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 12 October 2023.
All research outputs
#948,140
of 25,138,857 outputs
Outputs from BioMedical Engineering OnLine
#13
of 862 outputs
Outputs of similar age
#24,127
of 470,281 outputs
Outputs of similar age from BioMedical Engineering OnLine
#2
of 5 outputs
Altmetric has tracked 25,138,857 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 96th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 862 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.3. This one has done particularly well, scoring higher than 98% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 470,281 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 94% of its contemporaries.
We're also able to compare this research output to 5 others from the same source and published within six weeks on either side of this one. This one has scored higher than 3 of them.