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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Natural resistance to ascorbic acid induced oxidative stress is mainly mediated by catalase activity in human cancer cells and catalase-silencing sensitizes to oxidative stress
|
|---|---|
| Published in |
BMC Complementary Medicine and Therapies, May 2012
|
| DOI | 10.1186/1472-6882-12-61 |
| Pubmed ID | |
| Authors |
Christoph Klingelhoeffer, Ulrike Kämmerer, Monika Koospal, Bettina Mühling, Manuela Schneider, Michaela Kapp, Alexander Kübler, Christoph-Thomas Germer, Christoph Otto |
| Abstract |
Ascorbic acid demonstrates a cytotoxic effect by generating hydrogen peroxide, a reactive oxygen species (ROS) involved in oxidative cell stress. A panel of eleven human cancer cell lines, glioblastoma and carcinoma, were exposed to serial dilutions of ascorbic acid (5-100 mmol/L). The purpose of this study was to analyse the impact of catalase, an important hydrogen peroxide-detoxifying enzyme, on the resistance of cancer cells to ascorbic acid mediated oxidative stress. |
X Demographics
The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 2 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 2 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 79 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Hungary | 1 | 1% |
| Portugal | 1 | 1% |
| Denmark | 1 | 1% |
| Unknown | 76 | 96% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Bachelor | 15 | 19% |
| Student > Ph. D. Student | 13 | 16% |
| Student > Master | 12 | 15% |
| Researcher | 4 | 5% |
| Professor > Associate Professor | 4 | 5% |
| Other | 15 | 19% |
| Unknown | 16 | 20% |
| Readers by discipline | Count | As % |
|---|---|---|
| Biochemistry, Genetics and Molecular Biology | 14 | 18% |
| Agricultural and Biological Sciences | 13 | 16% |
| Medicine and Dentistry | 12 | 15% |
| Engineering | 4 | 5% |
| Pharmacology, Toxicology and Pharmaceutical Science | 4 | 5% |
| Other | 13 | 16% |
| Unknown | 19 | 24% |
Attention Score in Context
This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 09 September 2017.
All research outputs
#13,864,864
of 22,665,794 outputs
Outputs from BMC Complementary Medicine and Therapies
#1,605
of 3,617 outputs
Outputs of similar age
#94,806
of 163,462 outputs
Outputs of similar age from BMC Complementary Medicine and Therapies
#56
of 131 outputs
Altmetric has tracked 22,665,794 research outputs across all sources so far. This one is in the 37th percentile – i.e., 37% of other outputs scored the same or lower than it.
So far Altmetric has tracked 3,617 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 8.5. This one has gotten more attention than average, scoring higher than 53% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 163,462 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 41st percentile – i.e., 41% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 131 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 54% of its contemporaries.