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Effects of human intravenous immunoglobulin on amyloid pathology and neuroinflammation in a mouse model of Alzheimer’s disease

Overview of attention for article published in Journal of Neuroinflammation, May 2012
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1 tweeter

Citations

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56 Mendeley
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Title
Effects of human intravenous immunoglobulin on amyloid pathology and neuroinflammation in a mouse model of Alzheimer’s disease
Published in
Journal of Neuroinflammation, May 2012
DOI 10.1186/1742-2094-9-105
Pubmed ID
Authors

Lakshman Puli, Yuriy Pomeshchik, Katja Olas, Tarja Malm, Jari Koistinaho, Heikki Tanila

Abstract

Human intravenous immunoglobulin (hIVIG) preparation is indicated for treating primary immunodeficiency disorders associated with impaired humoral immunity. hIVIG is known for its anti-inflammatory properties and a decent safety profile. Therefore, by virtue of its constituent natural anti-amyloid beta antibodies and anti-inflammatory effects, hIVIG is deemed to mediate beneficial effects to patients of Alzheimer's disease (AD). Here, we set out to explore the effects of hIVIG in a mouse model of AD.

Twitter Demographics

The data shown below were collected from the profile of 1 tweeter who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 56 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Spain 1 2%
Unknown 55 98%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 10 18%
Researcher 8 14%
Student > Doctoral Student 6 11%
Student > Bachelor 5 9%
Student > Master 5 9%
Other 13 23%
Unknown 9 16%
Readers by discipline Count As %
Neuroscience 13 23%
Medicine and Dentistry 13 23%
Agricultural and Biological Sciences 12 21%
Biochemistry, Genetics and Molecular Biology 3 5%
Pharmacology, Toxicology and Pharmaceutical Science 1 2%
Other 4 7%
Unknown 10 18%

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 29 May 2012.
All research outputs
#2,897,780
of 3,633,617 outputs
Outputs from Journal of Neuroinflammation
#417
of 533 outputs
Outputs of similar age
#52,706
of 72,750 outputs
Outputs of similar age from Journal of Neuroinflammation
#36
of 46 outputs
Altmetric has tracked 3,633,617 research outputs across all sources so far. This one is in the 2nd percentile – i.e., 2% of other outputs scored the same or lower than it.
So far Altmetric has tracked 533 research outputs from this source. They receive a mean Attention Score of 3.0. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 72,750 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 46 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.