@kidney_boy Also, there's been reasonable argument that SCD may not be a great proxy for QT-related arrhythmias specifically. But more SCD is more SCD so I'd want to glance at how groups were balanced in the trial. https://t.co/jpwaqdXU7u https://t.co/7
6/ QT prolonging meds & SCD association - found that ppl more actually likely to die of underlying cause than arrhythmic death-confounding by indication: https://t.co/0MtpK0TZIi He then examined pts w/ HIV & SCD in HIV POST SCD Study, published i
”The range of exposure to QTPM increased the odds of nonarrhythmic death from 2.8- to 14.2-fold in a…exposure-dependent manner. In contrast, not even the highest exposure to QTPM translated to a statistically significant increased odds of autopsy-defined S
@dawso007 @MarkOldhamMD Are we really better off by putting so much emphasis on qt-prolongation? I can't forget this study. This suggests that a lot of the qt-prolongation causes of death is confounded. https://t.co/uMS2vLTWu6