RT @AntGDuarte: Tang et al concluded that ~30% of their 103 genomes were lin A. Now that's a big difference from 1 out of 27 in their Wuhan…
RT @AntGDuarte: Peter's favorite visualization of early genomes (green=lineage A, blue=lin.B) immediately reminded me of an old thread in w…
RT @AntGDuarte: SARS-CoV-2 lineages were first defined by Tang et al. 2020 according to differences in genomic positions 8782 and 28144. L…
RT @AntGDuarte: SARS-CoV-2 lineages were first defined by Tang et al. 2020 according to differences in genomic positions 8782 and 28144. L…
RT @AntGDuarte: Peter's favorite visualization of early genomes (green=lineage A, blue=lin.B) immediately reminded me of an old thread in w…
RT @AntGDuarte: Tang et al concluded that ~30% of their 103 genomes were lin A. Now that's a big difference from 1 out of 27 in their Wuhan…
RT @AntGDuarte: Peter's favorite visualization of early genomes (green=lineage A, blue=lin.B) immediately reminded me of an old thread in w…
Tang et al concluded that ~30% of their 103 genomes were lin A. Now that's a big difference from 1 out of 27 in their Wuhan subset. How could that be when most of their non-Wuhan seqs were still from people infected in Wuhan even if sampled elsewhere? 4/🧵
Peter's favorite visualization of early genomes (green=lineage A, blue=lin.B) immediately reminded me of an old thread in which I dissected a similar figure from Tang et al. 2020, a pioneering analysis of the 2 early lineages (red=lin.A, blue=lin.B). https
@Whitey900 @cultured_spice Let’s pretend that living through it wasn’t enough to prove its existence, and humour you. https://t.co/ocGCU22KJp https://t.co/H42E9hUL5G https://t.co/hJi3rSm1rQ https://t.co/HYXXALr11q https://t.co/4nOxhXAyGw
RT @feline_cannon: In non-market theories, both of these strains would have had originate via zoonosis elsewhere and make their way back to…
In non-market theories, both of these strains would have had originate via zoonosis elsewhere and make their way back to the immediate vicinity of these live raccoon dogs prior to the disease being recognized internationally. https://t.co/DauCPhVVKU https
@user3425664 @stevenemassey Take a look at Tang et al https://t.co/aSCgzm7N8y
@ambientisland @RomanPParker @courtney_ljo @JohnBoweActor On the origin and continuing evolution of SARS-CoV-2 https://t.co/oeNTUcdhhR
@edwardcholmes That's also shown with 103 genomes here https://t.co/cgZXiYrnCv Dates of samples range from Dec 24 to Feb 5 (supp S1)
@BallouxFrancois I found this. It could be interesting to follow up on this. There is a difference in the epidemiological dynamics of these two lineages. B eventually replacing A. https://t.co/Bm8n0B21Xq https://t.co/oHoQiaKsHl
RT @stevenemassey: @WendyOrent The existence of more than 1 lineage does not predicate more than 1 spillover. Did all subsequent SARS2 line…
RT @stevenemassey: @WendyOrent The existence of more than 1 lineage does not predicate more than 1 spillover. Did all subsequent SARS2 line…
RT @stevenemassey: @WendyOrent The existence of more than 1 lineage does not predicate more than 1 spillover. Did all subsequent SARS2 line…
RT @stevenemassey: @WendyOrent The existence of more than 1 lineage does not predicate more than 1 spillover. Did all subsequent SARS2 line…
@WendyOrent The existence of more than 1 lineage does not predicate more than 1 spillover. Did all subsequent SARS2 lineages arise from spillover events ? I think not @Pouldeau61 's claim that Worobey et al found A and B is false, they were IDed by Tang
@WashburneAlex @gadboit @JaEsf @tony_vandongen @RicketRobin @marc_g_wathelet @MartinaSisters @VBruttel @Jikkyleaks @raqueltobes @AdrianJ44426152 Yes, they were T8782C and C28144T (leading to conversion of A -> B) The first is synonymous, the second pr
@healthbyjames The ridicule heaped on the first version of this Feb 25th, 2020 paper, which was later proven (quietly) to be spot-on, by the powers that be; it was obvious to me at that point that "science" wasn't the driving force. https://t.co/vJEy60pZAe
Although we found only 4% variability in genomic nucleotides between SARS-CoV-2 and a bat SARS-related coronavirus (SARSr-CoV; RaTG13), the difference at neutral sites was 17%, suggesting the divergence between the two viruses is much larger than https://
@Toonces13451094 @dfocosi @TRyanGregory @CorneliusRoemer @yunlong_cao @SolidEvidence @ewencallaway @kakape @EricTopol @K_G_Andersen @LongDesertTrain @DrEricDing It is worth noting, perhaps, this article was published March 3, 2020 • On the Origin and Con
RT @Frajud12: @FaridaHCampbell @FridaGhitis A similarity with SARS-CoV-2 genome, the closest ever found, was in Chinese bats & pangolins. A…
@FaridaHCampbell @FridaGhitis A similarity with SARS-CoV-2 genome, the closest ever found, was in Chinese bats & pangolins. A true "medical engineer" & "anti-infectious biopharm" should know that, since there's a truck load of medical publications
ここで過去をフリカエッターその1🎌😷🎌
RT @DavidBahry: @BiophysicsFL @RicketRob @pathogenetics I wouldn't expect epistasis between positions 8,782 and 28,144, because the 8,782 s…
@BiophysicsFL @RicketRob @pathogenetics I wouldn't expect epistasis between positions 8,782 and 28,144, because the 8,782 substitution is just a synonymous substitution anyway (https://t.co/dOBNxuBmFY; https://t.co/AnYZOr8Dza; lineages A and B used to be
RT @stevenemassey: @Florin_Uncovers I also remember the Rambaut group aggressively dismissing the notion that B was a more transmissible de…
@Florin_Uncovers I also remember the Rambaut group aggressively dismissing the notion that B was a more transmissible derivative of A, which was plausibly proposed in the Feb 2020 preprint of the paper 👇 https://t.co/ZrPKUvK113
@captainwonkish @charles_gaba @KyleMartinsen_ The Other thing: one of the first detailed examinations of the outbreak, research from Jan, 2020, had access to some data that was later deleted, was attacked upon release, validated 6 months later. If you can
RT @Canned_Dinosaur: @yukitsugu1963 @unkotaberuno 2020年3月の時点で、変異のしやすさはしっかりとデータとして挙がってきています。また、インフルエンザワクチンの前例があるのに「予想は難しかった」は無理があるかと思います。 ワ…
RT @Canned_Dinosaur: @yukitsugu1963 @unkotaberuno 2020年3月の時点で、変異のしやすさはしっかりとデータとして挙がってきています。また、インフルエンザワクチンの前例があるのに「予想は難しかった」は無理があるかと思います。 ワ…
RT @Canned_Dinosaur: @yukitsugu1963 @unkotaberuno 2020年3月の時点で、変異のしやすさはしっかりとデータとして挙がってきています。また、インフルエンザワクチンの前例があるのに「予想は難しかった」は無理があるかと思います。 ワ…
RT @Canned_Dinosaur: @yukitsugu1963 @unkotaberuno 2020年3月の時点で、変異のしやすさはしっかりとデータとして挙がってきています。また、インフルエンザワクチンの前例があるのに「予想は難しかった」は無理があるかと思います。 ワ…
RT @Canned_Dinosaur: @yukitsugu1963 @unkotaberuno 2020年3月の時点で、変異のしやすさはしっかりとデータとして挙がってきています。また、インフルエンザワクチンの前例があるのに「予想は難しかった」は無理があるかと思います。 ワ…
RT @Canned_Dinosaur: @yukitsugu1963 @unkotaberuno 2020年3月の時点で、変異のしやすさはしっかりとデータとして挙がってきています。また、インフルエンザワクチンの前例があるのに「予想は難しかった」は無理があるかと思います。 ワ…
RT @Canned_Dinosaur: @yukitsugu1963 @unkotaberuno 2020年3月の時点で、変異のしやすさはしっかりとデータとして挙がってきています。また、インフルエンザワクチンの前例があるのに「予想は難しかった」は無理があるかと思います。 ワ…
RT @Canned_Dinosaur: @yukitsugu1963 @unkotaberuno 2020年3月の時点で、変異のしやすさはしっかりとデータとして挙がってきています。また、インフルエンザワクチンの前例があるのに「予想は難しかった」は無理があるかと思います。 ワ…
RT @Canned_Dinosaur: @yukitsugu1963 @unkotaberuno 2020年3月の時点で、変異のしやすさはしっかりとデータとして挙がってきています。また、インフルエンザワクチンの前例があるのに「予想は難しかった」は無理があるかと思います。 ワ…
RT @Canned_Dinosaur: @yukitsugu1963 @unkotaberuno 2020年3月の時点で、変異のしやすさはしっかりとデータとして挙がってきています。また、インフルエンザワクチンの前例があるのに「予想は難しかった」は無理があるかと思います。 ワ…
RT @Canned_Dinosaur: @yukitsugu1963 @unkotaberuno 2020年3月の時点で、変異のしやすさはしっかりとデータとして挙がってきています。また、インフルエンザワクチンの前例があるのに「予想は難しかった」は無理があるかと思います。 ワ…
RT @Canned_Dinosaur: @yukitsugu1963 @unkotaberuno 2020年3月の時点で、変異のしやすさはしっかりとデータとして挙がってきています。また、インフルエンザワクチンの前例があるのに「予想は難しかった」は無理があるかと思います。 ワ…
RT @Canned_Dinosaur: @yukitsugu1963 @unkotaberuno 2020年3月の時点で、変異のしやすさはしっかりとデータとして挙がってきています。また、インフルエンザワクチンの前例があるのに「予想は難しかった」は無理があるかと思います。 ワ…
RT @Canned_Dinosaur: @yukitsugu1963 @unkotaberuno 2020年3月の時点で、変異のしやすさはしっかりとデータとして挙がってきています。また、インフルエンザワクチンの前例があるのに「予想は難しかった」は無理があるかと思います。 ワ…
@yukitsugu1963 @unkotaberuno 2020年3月の時点で、変異のしやすさはしっかりとデータとして挙がってきています。また、インフルエンザワクチンの前例があるのに「予想は難しかった」は無理があるかと思います。 ワクチンが死者数を減らす最善の手段であったかも、何ら検証が無い状態(≒願望)かと。 https://t.co/Vwf1CLsnmY
@Rossana38510044 @_everythingism @MicahGoldrich @Biol4Ever @humourme101 @stuartjdneil @scotub @jaredpretender @InWuchang @Graybea71861266 @Stephengm99 @FrancescoEsp33 @past_is_future @CD57227 You simply didn't know what you were talking about RaTG13, both
@MJnanostretch What research literature suggests that RatG13 could be a direct progenitor of SARS2? I don't remember ever seeing any... The publication you cite suggests that RatG13 is actually MORE divergent from SARS2 than initially thought if u consider
RT @OttoKolbl: @dunklesritual @holmenkollin @BallouxFrancois Es gibt recht gute Forschung über die Mutationen des Virus, die besten papers…
RT @OttoKolbl: @dunklesritual @holmenkollin @BallouxFrancois Es gibt recht gute Forschung über die Mutationen des Virus, die besten papers…
@_hoeman @babarlelephant @emmecola @gdemaneuf Here's the link: https://t.co/ZrPKUvK113 If the market sequences were the (zoonotic) source of the epidemic, they should be in the center of the blue network (lineage B)
RT @Kevin_McKernan: @EthicalSkeptic This paper has a divergence calculator placing other coronaviruses 20-50 years ago. https://t.co/r8h03Z…
RT @Kevin_McKernan: @EthicalSkeptic This paper has a divergence calculator placing other coronaviruses 20-50 years ago. https://t.co/r8h03Z…
@EthicalSkeptic This paper has a divergence calculator placing other coronaviruses 20-50 years ago. https://t.co/r8h03Zo9ut https://t.co/qiVm3X7tUa
@ThyRamMan I have a few more from early 2020. https://t.co/RrCzOXG6iC
@CarolinaGirlDJT @JohnDor57634012 “Viruses evolve and get weaker - which is the way they work.” What’s your definition of weaker? They mutate. SARS‑CoV‑2?l itself evolved from and earlier virus. https://t.co/u9vV7hPB5O
@sickathehighhat @_everythingism @stuartjdneil @MichaelWorobey @notoriousFIL "orf1ab, which encodes replicase/transcriptase, is required for viral genome replication and might also be important for viral pathogenesis" https://t.co/QEoa4vttjD
RT @Rossana38510044: @Ayjchan There are even nice papers published on this: "Thus, the neutral molecular divergence between SARS-CoV-2 and…
@Ayjchan There are even nice papers published on this: "Thus, the neutral molecular divergence between SARS-CoV-2 and RaTG13 is 14 times larger than that between humans and chimpanzees, and twice as large as that between humans and macaques." https://t.co/
@carrie_benton @30Kelsc @Scott_Wiggam Unlike you, this is the science I read. Try it you might learn actual facts. https://t.co/kHXZVKdeEh https://t.co/w2bbY3rCju https://t.co/VU37S3r5aL https://t.co/dA4qX7w0ba
RT @AntGDuarte: SARS-CoV-2 lineages were first defined by Tang et al. 2020 according to differences in genomic positions 8782 and 28144. L…
RT @AntGDuarte: SARS-CoV-2 lineages were first defined by Tang et al. 2020 according to differences in genomic positions 8782 and 28144. L…
Lineage S (like seen in related bat CoVs) has 8782T/28144C whereas 8782C/28144T defines lineage L, now fully dominant in humans. @AntGDuarte https://t.co/TXM6GW8Mce https://t.co/p2U0M6WIi9
RT @AntGDuarte: @babarlelephant @pathogenetics @lab_leak @franciscodeasis @virological_org @Daoyu15 Here it is the table with location deta…
RT @AntGDuarte: SARS-CoV-2 lineages were first defined by Tang et al. 2020 according to differences in genomic positions 8782 and 28144. L…
RT @AntGDuarte: SARS-CoV-2 lineages were first defined by Tang et al. 2020 according to differences in genomic positions 8782 and 28144. L…
@babarlelephant @pathogenetics @lab_leak @franciscodeasis @virological_org @Daoyu15 Here it is the table with location details. See also this tweet for more references on C/C or T/T genomes: https://t.co/WP17RZMXwm https://t.co/0ckyizBEMn
RT @AntGDuarte: SARS-CoV-2 lineages were first defined by Tang et al. 2020 according to differences in genomic positions 8782 and 28144. L…
https://t.co/uLNhy2KxRm 在一篇中國團隊的論文中可以看到大部分進行測序的都是L毒株, 而S(更古老)只測了一個(發現了27個) From: https://t.co/TEUXkizQUN https://t.co/kvORNn0JpG
RT @AntGDuarte: SARS-CoV-2 lineages were first defined by Tang et al. 2020 according to differences in genomic positions 8782 and 28144. L…
RT @AntGDuarte: SARS-CoV-2 lineages were first defined by Tang et al. 2020 according to differences in genomic positions 8782 and 28144. L…
RT @AntGDuarte: @lab_leak @virological_org @jbloom_lab Tang et al. 2020 says EPI_ISL_406592 is neither S or L lineage ("only 28144 mutated"…
@lab_leak @virological_org @jbloom_lab Tang et al. 2020 says EPI_ISL_406592 is neither S or L lineage ("only 28144 mutated"). https://t.co/m2m7kzkHxl China/WHO joint report, p. 79, Fig. 7 caption: "one viral genome that carried a C>T variant at site 8
@JCPEREZCODEX @xazalbert @CaudeHenrion @autrement_votre @PinsolleT @boutaour @andrebercoff 🤔 il y aurait eu 2 "Cov" au départ à Wuhan ? Se souvenir de ces vidéos où des pers. s'écroulaient dans la rue. Pas une embolie respiratoire mais thrombose vasculaire
SARS-CoV-2 lineages were first defined by Tang et al. 2020 according to differences in genomic positions 8782 and 28144. Lineage S (like seen in related bat CoVs) has 8782T/28144C whereas 8782C/28144T defines lineage L, now fully dominant in humans. http
RT @OttoKolbl: @Ticklicker56 There is also epidemiological and experimental evidence that earlier strains spread much more slowly. Why is a…
@Ticklicker56 There is also epidemiological and experimental evidence that earlier strains spread much more slowly. Why is all this ignored, when more evidence is coming online almost every month? https://t.co/rKuQnoMz9l https://t.co/W1R2sbsdYv
これらは発生初期にS型、L型などと呼ばれていたものですね。系統AがS型、系統BがL型です。 https://t.co/mKm0tCY13l
@fagmyer @HL3133 @OnAirCoop @TravisHepburn @megtirrell @NIHDirector This may be more recent: https://t.co/233L0qqMNM?
@gorlando5 @JudyLaTorre6 @mtgreenee https://t.co/522Rktv4L1 https://t.co/PgJ3wPSBlR https://t.co/63qGAF5T90 Debate it. Refute it. Here, if you need some help here’s a good starting point. Try not to use whatever deep web conspiracy site you were and lo
RT @AtomsksSanakan: 4/H The viruses are related cousins, not one descended from the other. "the difference at neutral sites was 17%, sugg…
4/H The viruses are related cousins, not one descended from the other. "the difference at neutral sites was 17%, suggesting the divergence between the two viruses [RatG13 and SARS-CoV-2] is much larger than previously estimated." https://t.co/54v3b3TWUX
@scotub @FrancescoEsp33 @franciscodeasis @stuartjdneil @Rossana38510044 @InWuchang @krylormaximus @past_is_future @_everythingism @evolving_string @Daoyu15 @zhihuachen @ydeigin @lab_leak @JamieMetzl "the difference at neutral sites was 17%, suggesting the
RT @abledoc: The viruses isolated during the early phase of COVID19 in Wuhan already had 3 mutations different from its purported anteceden…
RT @abledoc: Chinese scientists led by Ming Wang continued to publish results referencing these sequence data, which suggests they were for…
RT @abledoc: The viruses isolated during the early phase of COVID19 in Wuhan already had 3 mutations different from its purported anteceden…
RT @abledoc: Chinese scientists led by Ming Wang continued to publish results referencing these sequence data, which suggests they were for…
Chinese scientists led by Ming Wang continued to publish results referencing these sequence data, which suggests they were forced to delete data that was inconvenient to the official narrative. https://t.co/5JG0qMLLXx
RT @abledoc: The viruses isolated during the early phase of COVID19 in Wuhan already had 3 mutations different from its purported anteceden…
On était déjà rendu à 3 variants au début de la pandémie. (Science mag)