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Dopamine Induced Neurodegeneration in a PINK1 Model of Parkinson's Disease

Overview of attention for article published in PLOS ONE, May 2012
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About this Attention Score

  • Good Attention Score compared to outputs of the same age (68th percentile)
  • Above-average Attention Score compared to outputs of the same age and source (63rd percentile)

Mentioned by

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1 X user
patent
1 patent

Citations

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68 Dimensions

Readers on

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111 Mendeley
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1 CiteULike
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Title
Dopamine Induced Neurodegeneration in a PINK1 Model of Parkinson's Disease
Published in
PLOS ONE, May 2012
DOI 10.1371/journal.pone.0037564
Pubmed ID
Authors

Sonia Gandhi, Annika Vaarmann, Zhi Yao, Michael R. Duchen, Nicholas W. Wood, Andrey Y. Abramov

Abstract

Parkinson's disease is a common neurodegenerative disease characterised by progressive loss of dopaminergic neurons, leading to dopamine depletion in the striatum. Mutations in the PINK1 gene cause an autosomal recessive form of Parkinson's disease. Loss of PINK1 function causes mitochondrial dysfunction, increased reactive oxygen species production and calcium dysregulation, which increases susceptibility to neuronal death in Parkinson's disease. The basis of neuronal vulnerability to dopamine in Parkinson's disease is not well understood.

X Demographics

X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 111 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Germany 2 2%
United Kingdom 2 2%
Australia 1 <1%
Italy 1 <1%
India 1 <1%
United States 1 <1%
Unknown 103 93%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 29 26%
Student > Bachelor 16 14%
Researcher 15 14%
Student > Master 11 10%
Professor 6 5%
Other 20 18%
Unknown 14 13%
Readers by discipline Count As %
Agricultural and Biological Sciences 37 33%
Neuroscience 18 16%
Biochemistry, Genetics and Molecular Biology 13 12%
Engineering 9 8%
Medicine and Dentistry 9 8%
Other 9 8%
Unknown 16 14%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 4. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 01 December 2020.
All research outputs
#6,912,452
of 22,668,244 outputs
Outputs from PLOS ONE
#81,356
of 193,511 outputs
Outputs of similar age
#49,198
of 164,788 outputs
Outputs of similar age from PLOS ONE
#1,296
of 3,777 outputs
Altmetric has tracked 22,668,244 research outputs across all sources so far. This one has received more attention than most of these and is in the 68th percentile.
So far Altmetric has tracked 193,511 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 15.0. This one has gotten more attention than average, scoring higher than 56% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 164,788 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 68% of its contemporaries.
We're also able to compare this research output to 3,777 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 63% of its contemporaries.