↓ Skip to main content
Embed badge What is this page?

Anti-inflammatory activity and neutrophil reductions mediated by the JAK1/JAK3 inhibitor, CP-690,550, in rat adjuvant-induced arthritis

Overview of attention for article published in Journal of Inflammation, January 2010
Altmetric Badge

About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • One of the highest-scoring outputs from this source (#10 of 367)
  • High Attention Score compared to outputs of the same age (95th percentile)
  • High Attention Score compared to outputs of the same age and source (90th percentile)

Mentioned by

blogs
1 blog
twitter
1 tweeter
patent
3 patents
facebook
1 Facebook page

Citations

dimensions_citation
366 Dimensions

Readers on

mendeley
202 Mendeley

What is this page?

Summary Blogs Twitter Patents Facebook Dimensions citations
You are seeing a free-to-access but limited selection of the activity Altmetric has collected about this research output. Click here to find out more.
Title
Anti-inflammatory activity and neutrophil reductions mediated by the JAK1/JAK3 inhibitor, CP-690,550, in rat adjuvant-induced arthritis
Published in
Journal of Inflammation, January 2010
DOI 10.1186/1476-9255-7-41
Pubmed ID
20701804
Authors

Debra M Meyer, Michael I Jesson, Xiong Li, Mollisa M Elrick, Christie L Funckes-Shippy, James D Warner, Cindy J Gross, Martin E Dowty, Shashi K Ramaiah, Jeffrey L Hirsch, Matthew J Saabye, Jennifer L Barks, Nandini Kishore, Dale L Morris

Abstract

The Janus kinase (JAK) family of tyrosine kinases includes JAK1, JAK2, JAK3 and TYK2, and is required for signaling through Type I and Type II cytokine receptors. CP-690,550 is a potent and selective JAK inhibitor currently in clinical trials for rheumatoid arthritis (RA) and other autoimmune disease indications. In RA trials, dose-dependent decreases in neutrophil counts (PBNC) were observed with CP-690,550 treatment. These studies were undertaken to better understand the relationship between JAK selectivity and PBNC decreases observed with CP-690,550 treatment.

View on publisher site

Twitter Demographics

The data shown below were collected from the profile of 1 tweeter who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 202 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Portugal 1 <1%
Brazil 1 <1%
India 1 <1%
Argentina 1 <1%
Spain 1 <1%
Japan 1 <1%
United States 1 <1%
Unknown 195 97%

Demographic breakdown

Readers by professional status Count As %
Researcher 45 22%
Student > Ph. D. Student 25 12%
Student > Master 25 12%
Other 22 11%
Student > Bachelor 19 9%
Other 29 14%
Unknown 37 18%
Readers by discipline Count As %
Medicine and Dentistry 44 22%
Agricultural and Biological Sciences 40 20%
Biochemistry, Genetics and Molecular Biology 23 11%
Pharmacology, Toxicology and Pharmaceutical Science 15 7%
Chemistry 15 7%
Other 16 8%
Unknown 49 24%

Attention Score in Context

This research output has an Altmetric Attention Score of 19. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 28 July 2021.
All research outputs
#1,698,315
of 22,899,952 outputs
Outputs from Journal of Inflammation
#10
of 367 outputs
Outputs of similar age
#8,066
of 164,231 outputs
Outputs of similar age from Journal of Inflammation
#1
of 11 outputs
Altmetric has tracked 22,899,952 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 92nd percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 367 research outputs from this source. They receive a mean Attention Score of 4.3. This one has done particularly well, scoring higher than 97% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 164,231 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 95% of its contemporaries.
We're also able to compare this research output to 11 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 90% of its contemporaries.

This page is provided by Altmetric.