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MicroRNAs and hepatitis C virus: Toward the end of miR-122 supremacy

Overview of attention for article published in Virology Journal, June 2012
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Title
MicroRNAs and hepatitis C virus: Toward the end of miR-122 supremacy
Published in
Virology Journal, June 2012
DOI 10.1186/1743-422x-9-109
Pubmed ID
Authors

Thomas Walter Hoffmann, Duverlie Gilles, Bengrine Abderrahmane

Abstract

The most common etiologic agents causing chronic hepatitis are hepatitis C and B viruses (HCV and HBV, respectively). Chronic infection caused by HCV is considered one of the major causative agents of liver cirrhosis and hepatocellular carcinoma worldwide. In combination with the increasing rate of new HCV infections, the lack of a current vaccine and/or an effective treatment for this virus continues to be a major public health challenge. The development of new treatments requires a better understanding of the virus and its interaction with the different components of the host cell. MicroRNAs (miRNAs) are small non-coding RNAs functioning as negative regulators of gene expression and represent an interesting lead to study HCV infection and to identify new therapeutic targets. Until now, microRNA-122 (miR-122) and its implication in HCV infection have been the focus of different published studies and reviews. Here we will review recent advances in the relationship between HCV infection and miRNAs, showing that some of them emerge in publications as challengers against the supremacy of miR-122.

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X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 77 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 2 3%
Japan 1 1%
Netherlands 1 1%
Germany 1 1%
Unknown 72 94%

Demographic breakdown

Readers by professional status Count As %
Researcher 18 23%
Student > Master 13 17%
Student > Ph. D. Student 12 16%
Professor > Associate Professor 9 12%
Student > Doctoral Student 8 10%
Other 15 19%
Unknown 2 3%
Readers by discipline Count As %
Agricultural and Biological Sciences 31 40%
Medicine and Dentistry 14 18%
Biochemistry, Genetics and Molecular Biology 13 17%
Immunology and Microbiology 6 8%
Pharmacology, Toxicology and Pharmaceutical Science 4 5%
Other 4 5%
Unknown 5 6%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 13 June 2012.
All research outputs
#20,159,700
of 22,668,244 outputs
Outputs from Virology Journal
#2,863
of 3,029 outputs
Outputs of similar age
#151,149
of 167,155 outputs
Outputs of similar age from Virology Journal
#40
of 50 outputs
Altmetric has tracked 22,668,244 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.
So far Altmetric has tracked 3,029 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 25.5. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
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