Title |
Collagen fibre implant for tendon and ligament biological augmentation. In vivo study in an ovine model
|
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Published in |
Knee Surgery, Sports Traumatology, Arthroscopy, June 2012
|
DOI | 10.1007/s00167-012-2102-7 |
Pubmed ID | |
Authors |
Davide Enea, Jessica Gwynne, Simon Kew, Meera Arumugam, Jennifer Shepherd, Roger Brooks, Siddhartha Ghose, Serena Best, Ruth Cameron, Neil Rushton |
Abstract |
Although most in vitro studies indicate that collagen is a suitable biomaterial for tendon and ligament tissue engineering, in vivo studies of implanted collagen for regeneration of these tissues are still lacking. The objectives of this study were the following: (1) to investigate the regeneration of the central third of the ovine patellar tendon using implants made of an open array of collagen fibres (reconstituted, extruded bovine collagen); and (2) to compare two collagen crosslinking chemistries: carbodiimide and carbodiimide associated with ethyleneglycoldiglycidylether. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
United Kingdom | 1 | 100% |
Demographic breakdown
Type | Count | As % |
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Practitioners (doctors, other healthcare professionals) | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 1 | 2% |
Unknown | 44 | 98% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 8 | 18% |
Student > Master | 8 | 18% |
Researcher | 7 | 16% |
Student > Doctoral Student | 5 | 11% |
Student > Bachelor | 3 | 7% |
Other | 5 | 11% |
Unknown | 9 | 20% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 14 | 31% |
Agricultural and Biological Sciences | 8 | 18% |
Engineering | 7 | 16% |
Biochemistry, Genetics and Molecular Biology | 3 | 7% |
Materials Science | 2 | 4% |
Other | 0 | 0% |
Unknown | 11 | 24% |