Though treatment of #neuroblastoma has remained elusive, research indicates that a partially deleted chromosome 11 is a contributor. This @BioMedCentral study focuses on one gene in particular, and how its absence could be linked to this childhood #cancer:
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Forskarna har upptäckt att genen DLG2 delvis har förlorats genom 11q-deletion, eller tryckts ner genom MYCN-amplifiering, i aggressiva tumörer, vilket ökar celldelningshastigheten. Läs studien på https://t.co/bOFOZMSAhq
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Low DLG2 gene expression, a link between 11q-deleted and MYCN-amplified neuroblastoma, causes forced cell cycle progression, and predicts poor patient survival https://t.co/pO0nc4KRxp