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Co-circulation of two genotypes of dengue virus serotype 3 in Guangzhou, China, 2009

Overview of attention for article published in Virology Journal, January 2012
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Title
Co-circulation of two genotypes of dengue virus serotype 3 in Guangzhou, China, 2009
Published in
Virology Journal, January 2012
DOI 10.1186/1743-422x-9-125
Pubmed ID
Authors

Tao Jiang, Xue-Dong Yu, Wen-Xin Hong, Wei-Ze Zhou, Man Yu, Yong-Qiang Deng, Shun-Ya Zhu, E-De Qin, Jian Wang, Cheng-Feng Qin, Fu-Chun Zhang

Abstract

Dengue is emerging as the most important mosquito borne viral disease in the world. In mainland China, sporadic and large outbreaks of dengue illness caused by the four serotypes of dengue virus (DENV-1 to DENV-4) have been well documented. Guangdong province is the major affected area in China, and DENV-1 has dominantly circulated in Guangdong for a long time. In this study, a family cluster of DENV-3 infection in Guangzhou was described. Three cases were diagnosed as dengue fever based on clinical manifestation, serological and RT-PCR assays. Two DENV-3 strains were isolated in C6/36 cells and the complete genome sequences were determined. Phylogenetic analysis revealed that the new DENV-3 isolates from the family cluster were grouped within genotype III. Considering the fact that several DENV-3 strains within genotype V were also identified in Guangzhou in 2009, at least two genotypes of DENV-3 co-circulated in Guangzhou. Careful investigation and virological analysis should be warranted in the future.

Mendeley readers

The data shown below were compiled from readership statistics for 41 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 2 5%
Unknown 39 95%

Demographic breakdown

Readers by professional status Count As %
Researcher 10 24%
Student > Ph. D. Student 7 17%
Student > Master 6 15%
Student > Doctoral Student 5 12%
Unspecified 4 10%
Other 9 22%
Readers by discipline Count As %
Agricultural and Biological Sciences 15 37%
Medicine and Dentistry 7 17%
Unspecified 7 17%
Biochemistry, Genetics and Molecular Biology 4 10%
Immunology and Microbiology 2 5%
Other 6 15%