@aapee12 Tässä vielä sokerina pohjalla yksi niistä, joissa on katsottu myös oikeasti "elävää" virusta ihmisistä ennen oireiden alkua, eikä pelkästään PCR:ää. https://t.co/woQR8gm92n
無症状期の感染リスクについてはこちらを参考にすべきでしょう。 https://t.co/V8FtHBIc2Y
@EWidera https://t.co/JLroREBgbD This article was instrumental in our understanding of transmission of SARS-CoV-2 in skilled nursing facilities and had immediate policy implications
RT @PauloEastvan: @Lidsville "The accelerated doubling time was likely to have been due to inadequately controlled intrafacility transmissi…
@Lidsville "The accelerated doubling time was likely to have been due to inadequately controlled intrafacility transmission...high viral titers from the respiratory tract, including shedding before the onset of symptoms...droplet and possibly aerosol trans
RT @mugecevik: 14/ In a nursing home facility, 23d after the first resident with #COVID19, among 84 residents (76 tested), 48 were positive…
@Die_Diktatur @BorgerPieter @Andre_van_Z @c_drosten @vmcorman @MarionKoopmans @hugodejonge @rivm Whoa, the screenshot was from the paper YOU brought in. Even they do not deny presympt. transmission. You chose to blindly trust the paper. Now you question it
RT @tyonarock: NEJM 高齢者施設の感染拡大について 主に発症前の無症状時期にウイルスを媒介している。 感染力が最も強いのが症状発現前。 つまり、感染拡大制御が目的であれば、症状がでてからのPCRや隔離はそれほど意味がない(意味がないわけじゃないけど)。…
@AndersEngstrm4 @ar_covid @matsxekberg @Folkhalsomynd Här odlar man viruset både från individer före de får symptom och från individer som helt saknar symptom under hela infektionsförloppet. Jag har även länkat till korrelat mellan odling och PCR ovan. h
@AndersEngstrm4 @ar_covid @matsxekberg @Folkhalsomynd Därtill blandar många ihop presymptomatisk och rent asymptomatisk smitta. Även om helt asymptomatisk smitta skulle vara mindre betydelsefull så beräknas upp mot hälften av smittan som nämns högst upp i
@You3_JP Ct値35以上で分離培養 https://t.co/pN6wQ3ocCI Ct値34以上で分離培養 https://t.co/BOQDgdcHN1
RT @tyonarock: NEJM 高齢者施設の感染拡大について 主に発症前の無症状時期にウイルスを媒介している。 感染力が最も強いのが症状発現前。 つまり、感染拡大制御が目的であれば、症状がでてからのPCRや隔離はそれほど意味がない(意味がないわけじゃないけど)。…
RT @FORCEPS4: 「症状のない陽性者からは伝染しない」という主張がTLに流れてくるのですが、無症状期の感染性を示した論文です。 https://t.co/V8FtHBIc2Y
「症状のない陽性者からは伝染しない」という主張がTLに流れてくるのですが、無症状期の感染性を示した論文です。 https://t.co/V8FtHBIc2Y
@MarshalTheWill1 @GlennHaworth @ChrisHall250TPI @ClarkeMicah I'm sure its not this one because this suggest a major role for asymptomatic/ presymptomatic spread https://t.co/UZeMBkc0ua
@rotewolle Ich bezog mich bei all dem ja nur auf die wenigen tatsächlich Asymptomatischen. Transmission ohne Symptome findet daneben zu einem erheblichen Teil durch Präsymptomatische statt (siehe z.B. oben Buitrago-Garcia et al., bestätigend https://t.co/k
@Rickinthewall Your study references this one, for example.. https://t.co/ehEdwPvB8r
@BillSpadea This is absolutely not true. Studies show that asymptomatic and presymptomatic transmission of SARS-CoV-2 is occurring. https://t.co/pvRyAnxv7U
@erinhaust @justlikekevin @SandyShrimp @jhaskinscabrera @justin_hart Lol, "the actual study" contains the provided proviso. "Just for giggles", read up on the high infectivity of presymptomatics. https://t.co/jRMP6mRTC6 https://t.co/xC1VGUjcCZ https://t.
@_BrainWavez_ @jhaskinscabrera @TTBikeFit @garyricenc60 My point is that whether or not asymptomatic transmission is efficient, the presymptomatic period has been shown to include a period of high infectivity. It is a difficult period to study since it is
@LorenCharnley @jhaskinscabrera @Carlos79779805 @nay_sue1 The rationale comes from studies like these: In a facility of 89, 24 were presymptomatic & 24 were asymptomatic. 11 hospitalized. 15 died. Focusing "solely on symptomatic residents [was] not s
@aloa5 @axiom4tic @Tim_Maloy Aber in Ref. 5 findet sich gar keine solche Behauptung, soweit ich das sehen kann. Eher im Gegenteil: "More than half of residents with positive test results were asymptomatic at the time of testing and most likely contributed
@LorenCharnley @jhaskinscabrera @nay_sue1 Admittedly a close contact setting but ... In a facility of 89, 24 were asymptomatic & 24 were presymptomatic. 11 hospitalized. 15 died. "Infection-control strategies focused solely on symptomatic residents we
@BjStov @JustTheTweets17 @washingtonpost In a facility of where 24 of 89 residents were asymptomatic & 24 were presymptomatic, 11 were hospitalized & 15 died. "Infection-control strategies focused solely on symptomatic residents were not sufficien
@law_and_peace @AtomsksSanakan @NightWatchman21 @AeonCoin @seaport1961 @DrEricDing @zorinaq @thereal_truther @DraganOrlich @greg_travis @EauxSnap @CHOMES102 Except that focusing on symptomatics only does not contain outbreaks. "Infection-control strategie
@daffodil_hippo @john77994979 @BrandonStraka Link? I’ve been reconsidering pre-symptomatic spread but haven’t read much recently. Previously I’d considered https://t.co/IojVd4orWY to be strong evidence of pre-symp spread.
@HelGe82034378 @jens140180 @hendrikstreeck Das Papier sagt selbst „ein relevanter Teil“ steckt sich präsymptomatisch an. Das sie eine Rolle im Infektionsgeschehen spielen, wurde aber schon in frühen Studien festgestellt. BeispielStudie dazu siehe auch oben
@HelGe82034378 @jens140180 @hendrikstreeck … nicht feststellen, bevor Symptome auftreten. Siehe aber bspw hier: https://t.co/gypQtpfMok
@ds13_manon @SoSlickMedia @Ravenshead2222 Willful ignorance or you haven't looked: Covid has been grown in culture, genome sequenced and we have EM pictures of it In this study alone: https://t.co/31zlTt2OUK They "cultured" the virus (not PCR) in a majorit
12/X Since SARS-CoV-2 is very contagious (high R0 and therefore high HIT), SARS-CoV-2 then quickly infects a large proportion of people in smaller populations and/or populations covering small areas, before behavior changes and interventions limit spread
@DonaldWelsh16 His calculation ignores the possibility of being infected by someone who is presymptomatic which is much more probable. https://t.co/IWEbwDOm0x
@BrendanEich Like this one? https://t.co/td25cMuli2
@BrendanEich Taking a cursory look at the references finds this study from May. https://t.co/eCbRgHD9YU https://t.co/ta0XA4cMlg
@mbalimcdust Some people honestly chose to be ignorant in this age of information. Retching their underead opinions on the subject whilst several of the world's top Medical journals have taken down paywalls to allow public access to ongoing leading researc
@kharaguchi 控えめに言って、「症状が出る直前か直後」に最大の感染力があるのは忽那先生の図の通りです Presymptomatic SARS-CoV-2 Infections and Transmission in a Skilled Nursing Facility | NEJM https://t.co/7csNyoB7b7
@TheRealSkriver @42_elliot #COVID19 #bcpoli #bced guys actually read the results and scientific references to understand not just the titles!! #StaySafe
Asymptomatic? Or Presymptomatic? https://t.co/VHKGkMv2h9
@nocompulsoryvac @TTBikeFit Here is an article from early in the ~demic. It investigates a small number of people but nicely shows asymptomatic vs presymptomatic vs symptomatic along with cycle numbers and the ability to culture live virus. https://t.co/0
Among 76 residents who participated in point-prevalence surveys, 48 (63%) tested positive. Of these 48 residents, 27 (56%) were asymptomatic at the time of testing; 24 subsequently developed symptoms (median time to onset, 4 days). https://t.co/GZq5qS9kiS
@PolyandS @LouisianaGov Because apparently doing a little research is hard - from the gold standard of US medical science journals: “Of these 48 residents, 27 (56%) were asymptomatic at the time of testing; 24 subsequently developed symptoms (median time t
@gerdantes Und gerne mit Berücksichtigung der Symptomatik und Zellkultur als Referenz. Tricky ist nur, dass auch die Sars-Cov-2-Negativen (abhängig vom Beobachtungszeitraum) häufig symptomatisch sind... https://t.co/nRs0htC5tT https://t.co/HItC7YPLJD
@wrightjeff @jeffreyatucker @aier OK, but as always the less informed people regularly mix up "asymptomatic" (never developing symptoms) and "presymptomatic" (early days during infection before developing symptoms). See for example here: https://t.co/SGnol
@ortis78 @sofalakatino78 @UdiQimron "א-סימפטומטיים אינם מדבקים" - הנה מחקר שמוכיח ההיפך: https://t.co/1yWHjoYxaS
@WorstAtRoutine @rotewolle @degampraesident Die Autoren des ursprünglichen Artikels interpretieren die Daten auch deutlich zurückhaltender - und letztendlich waren 89% der Asymptomatischen am Ende doch symptomatisch (wobei auch die negativen Getesteten häu
RT @ID_ethics: Also here is viable virus by culture (red) versus non-viable (black) at different cycle thresholds (proxy for viral load) an…
Also here is viable virus by culture (red) versus non-viable (black) at different cycle thresholds (proxy for viral load) and day of symptoms Study found no difference in viral load between symptomatic, presymptomatic and asymptomatic cases 2/2 https://
@DrJinRussell @SiouxsieW There's this NEJM study of a nursing home with 24 of 49 tested 6 days after a negative result converting to positive. https://t.co/guFcNUn6RL
@WorstAtRoutine @degampraesident Der Original-Artikel ⬇️ ist tatsächlich interessant. Demnach waren 89% der "Asymptomatischen" letztendlich doch symptomatisch. 🤷 Wobei die Kontrolle ebenfalls sehr symptomatisch ist. https://t.co/nRs0htC5tT
@Baloo24 @lilaEmma5 @drluebbers Danke. Hieraus zu schließen, dass asymptomatische NICHT infektiös sind, ist eine steile These. Zumal nicht klar ist, ob da die presymptomatischen inkludiert sind. Ich wäre mit solchen Aussagen vorsichtig. https://t.co/N4Eyp
@Simplyt66442038 @jdevans141 @isabelrodbar Re: "Infection rates on ships never generally exceeded 20-25%" Stop trolling, denialist. https://t.co/7L0farMchQ
@MichaelYeadon3 And another one https://t.co/UFR9rd5ikM
@dkerr12345 @MichaelYeadon3 eg https://t.co/Sl8z4mag3U You may also find this paper interesting "Heterogeneity in transmissibility and shedding SARS-CoV-2 via droplets and aerosols" https://t.co/hQAkTE1zwW https://t.co/l1JK5CTaF4
RT @equibotanica: Symptom-based infection-control strategies are not sufficient to prevent transmission of SARS-CoV-2 in care settings. T…
RT @equibotanica: Symptom-based infection-control strategies are not sufficient to prevent transmission of SARS-CoV-2 in care settings. T…
@JuhanaSiljander @ArcDialtd näköjään jopa lupaillut tarjota testejä koekäyttöön. Liekö kukaan tarttunut?
@EKalmanen @MikaelNiku @reimatw @JonnaSodervall Epidemian hallinnassa tärkeintä on tutkimuskirjallisuuden mukaan testauksen frekevenssi ja tulosten nopeus. Herkkyys on toissijaista. Suurin osa vain PCR-positiivisista (ag-neg.) ei ole infektiivisiä, kun näy
-> ... även om risken för smitta från asymptomatiska individer tycks lägre än från de med symptom. Urval av referenser: Presymptomatisk smitta: https://t.co/9msJ1E8axx & https://t.co/WVnV4fbfm0 & https://t.co/WNOU3AP25x & https://t.co/x0
@KatyDaly7 @ISAGCOVID19 @VictorianCHO @stephenjduckett @JulienMercille @GabrielScally @astaines @IndependentSage @aoifemcl @TrishCork @yaneerbaryam Here a breakout in a nursing home was investigated, including virus sequencing and cell culturing: https://t
@KatyDaly7 @ISAGCOVID19 @VictorianCHO @stephenjduckett @JulienMercille @GabrielScally @astaines @IndependentSage @aoifemcl @TrishCork @yaneerbaryam Isolates and cell culture from humans: https://t.co/4tbdo9PgPJ https://t.co/HqoQhMh2Ee https://t.co/RiFc7r
@Socher41749744 @Panthea2019 @sanvenganz_a Virus Isolate: Bei einem Baby: https://t.co/HqoQhMh2Ee Bei einem US-Patienten: https://t.co/MglcczK8gK Bei mehren Patienten einer Pflegestation: https://t.co/RiFc7r0g9E und vielfach mehr ohne dass dies explizit
@migroxxx @velardedaoiz2 @ZapateroAntonio @eruizescudero @IdiazAyuso ¿Y de donde sacas que los presintomáticos tengan una carga viral más baja? Te dejo uno de los muchos ejemplos que muestran que la fase presintomática ya es infectiva y que la carga viral
RT @tyonarock: NEJM 高齢者施設の感染拡大について 主に発症前の無症状時期にウイルスを媒介している。 感染力が最も強いのが症状発現前。 つまり、感染拡大制御が目的であれば、症状がでてからのPCRや隔離はそれほど意味がない(意味がないわけじゃないけど)。…
RT @carpe_diem0820: 看護施設の有病率調査に参加した76人の居住者のうち、48人(63%)がSARS-CoV-2陽性、うち27人(56%)が検査時に無症状も、24人がその後に発症(中央値4日) →症候性対策では不十分 Presymptomatic SARS-…
RT @tyonarock: NEJM 高齢者施設の感染拡大について 主に発症前の無症状時期にウイルスを媒介している。 感染力が最も強いのが症状発現前。 つまり、感染拡大制御が目的であれば、症状がでてからのPCRや隔離はそれほど意味がない(意味がないわけじゃないけど)。…
RT @tyonarock: NEJM 高齢者施設の感染拡大について 主に発症前の無症状時期にウイルスを媒介している。 感染力が最も強いのが症状発現前。 つまり、感染拡大制御が目的であれば、症状がでてからのPCRや隔離はそれほど意味がない(意味がないわけじゃないけど)。…
RT @tyonarock: NEJM 高齢者施設の感染拡大について 主に発症前の無症状時期にウイルスを媒介している。 感染力が最も強いのが症状発現前。 つまり、感染拡大制御が目的であれば、症状がでてからのPCRや隔離はそれほど意味がない(意味がないわけじゃないけど)。…
RT @giovannilandoni: Here’re a few NEJM manuscripts explaining it plainly https://t.co/CMN1AUiFmq More than half of residents with positive…
Here’re a few NEJM manuscripts explaining it plainly https://t.co/CMN1AUiFmq More than half of residents with positive test results were asymptomatic at the time of testing and most likely contributed to transmission 2/
@Kessy19721 @florianaigner Wie ich Ihnen eben schon geschickt habe: https://t.co/PMjTefIWll und https://t.co/uvozCTsWP2
Tutkimukset viittaavat vahvasti siihen, että eniten virusta levittävät COVID-19-tapaukset saataisiin kiinni myös antigeenitesteillä jo ennen oireiden alkua (mm. Arons ym. 2020, kuva 2). Tutkittaisiinko suomalaisvoimin miten asia on? Me tarjoamme testit! ht
@AndrewBastian16 @RhysClark97 @CAtoNY8965 @SiegelForTexas Why is it that you disagree with a symptomatic spread? Is this a belief you have or based on empirical/statistical evidence? https://t.co/aJfiZCNsyJ
RT @EricMeyerowitz: 1/ Apropos of nothing (cc @AaronRichterman), a few studies on duration of isolation of live virus following symptom ons…
RT @EricMeyerowitz: 1/ Apropos of nothing (cc @AaronRichterman), a few studies on duration of isolation of live virus following symptom ons…
1/ Apropos of nothing (cc @AaronRichterman), a few studies on duration of isolation of live virus following symptom onset in people with COVID-19. In this study from a Washington nursing home, live virus was cultured up to 9 days after symptom onset http
@annabelmachadoo @lileaasy Janela dos exames: https://t.co/JZoRdkV0pS https://t.co/nOF4mKbc9o Assintomáticos e oligossintomatico: https://t.co/VpSFbFLAFU https://t.co/FZOUKBzLWN https://t.co/TxvKyS7U5h Transmissão antes dos sintomas: https://t.co/SUiZZ
(Another: https://t.co/Hu0qCeixHy)
@AgnesWold @bjornpiltz @KennethBodin @FallTove @JacobGudiol @LU_Jonas_Bjork Metastudien refererade även till denna: "Ct values for the four symptom status groups were similar (asymptomatic residents, 25.5; presymptomatic residents, 23.1; residents with aty
bereits bei einem ct >24 oder einem Symptom onset to test (STT) von 8 Tagen fehlschlägt (=nicht mehr infektiös). Eine weitere Studie aus UK legt nahe, dass man auch bei präsymptomatischen praktikabel eine Grenze bei ct <=30 ziehen kann und dabei nur
RT @mugecevik: 14/ In a nursing home facility, 23d after the first resident with #COVID19, among 84 residents (76 tested), 48 were positive…
RT @mugecevik: 14/ In a nursing home facility, 23d after the first resident with #COVID19, among 84 residents (76 tested), 48 were positive…
@anitattam https://t.co/HCW6sZKbLB La mortalidad depende de muchos factores, pero aquí tienes un ejemplo de cómo focalizarse únicamente en los sintomáticos puede llevar a que el virus se expanda por todo un edificio y termine llevando a la UCI y matando a
Lo que dice la evidencia: los asintomáticos pueden ser contagiosos durante largos períodos; la carga viral detectada en casos asintomáticos es similar a la de otros casos sintomáticos. https://t.co/tQCUqCloOy https://t.co/g0AqkiHYYp
RT @nadnerb217: @m_adrians @TeresabDB62 @sunriseon7 @kochie_online @JennyMikakos Among 76 residents who participated in point-prevalence su…
@m_adrians @TeresabDB62 @sunriseon7 @kochie_online @JennyMikakos Among 76 residents who participated in point-prevalence surveys, 48 (63%) tested positive. Of these 48 residents, 27 (56%) were asymptomatic at the time of testing; 24 subsequently developed
@IAmFrankButcher @rtenews Don’t run away frank. https://t.co/NJn3j1QBuX
@IAmFrankButcher @rtenews That’s English frank. Have a read. https://t.co/NJn3j1QBuX
@IAmFrankButcher @rtenews Oh but I can, and no attempt to sprinkle some impressive medical terms over your effluent will work with me frank. Evidence speaks for itself. Stop digging. https://t.co/NJn3j1QBuX
@LawyerDave1 @EmilyPetro22 https://t.co/77uddjGwKg proves the incredible structural similarity https://t.co/zROtQ3wAo5 demonstrates type 1/3 interferon antagonism which likely explains the PRE-SYMPTOMATIC spread shown here: https://t.co/IojVd4orWY SARS-