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Benefit of a single recruitment maneuver after an apnea test for the diagnosis of brain death

Overview of attention for article published in Critical Care, July 2012
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Title
Benefit of a single recruitment maneuver after an apnea test for the diagnosis of brain death
Published in
Critical Care, July 2012
DOI 10.1186/cc11408
Pubmed ID
Authors

Marie Paries, Nicolas Boccheciampe, Mathieu Raux, Bruno Riou, Olivier Langeron, Armelle Nicolas-Robin

Abstract

ABSTRACT: INTRODUCTION: Many potential lung transplants are lost because of hypoxemia during donor management. We hypothesized that the apnea test, necessary to confirm the diagnosis of brain death in potential lung donors, was involved in the decrease in the ratio of partial pressure of arterial O2 to fraction of inspired O2 (PaO2/FiO2) and that a single recruitment maneuver performed just after the apnea test can reverse this alteration. METHODS: In this case-control study, we examined the effectiveness of the recruitment maneuver with a comparison cohort of brain dead patients who did not receive the maneuver. Patients were matched one-to-one on the basis of initial PaO2/FiO2 and on the duration of mechanical ventilation before the apnea test. PaO2/FiO2 was measured before (T1), at the end (T2) and two hours after apnea test (T3). RESULTS: Twenty-seven patients were included in each group. The apnea test was associated with a significant decrease in PaO2/FiO2 from 284 ± 98 to 224 ± 104 mmHg (P < 0.001). The decrease in PaO2/FiO2 between T1 and T3 was significantly lower in the recruitment maneuver group than in the control group (-4 (-68-57) vs -61 (-110--18) mmHg, P = 0.02). The number of potential donors with PaO2/FiO2 > 300 mmHg decreased by 58% (95% CI: 28-85%) in the control group vs 0% (95% CI: 0-34%) in the recruitment maneuver group (P < 0.001). CONCLUSIONS: The apnea test induced a decrease in PaO2/FiO2 in potential lung donors. A single recruitment maneuver performed immediately after the apnea test can reverse this alteration and may prevent the loss of potential lung donors.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 44 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Switzerland 1 2%
France 1 2%
Brazil 1 2%
Czechia 1 2%
Canada 1 2%
Unknown 39 89%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 6 14%
Researcher 6 14%
Other 5 11%
Student > Doctoral Student 4 9%
Professor 4 9%
Other 11 25%
Unknown 8 18%
Readers by discipline Count As %
Medicine and Dentistry 23 52%
Engineering 3 7%
Neuroscience 2 5%
Nursing and Health Professions 1 2%
Economics, Econometrics and Finance 1 2%
Other 3 7%
Unknown 11 25%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 10 July 2012.
All research outputs
#16,048,009
of 25,374,917 outputs
Outputs from Critical Care
#5,211
of 6,554 outputs
Outputs of similar age
#108,642
of 177,745 outputs
Outputs of similar age from Critical Care
#74
of 123 outputs
Altmetric has tracked 25,374,917 research outputs across all sources so far. This one is in the 34th percentile – i.e., 34% of other outputs scored the same or lower than it.
So far Altmetric has tracked 6,554 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 20.8. This one is in the 18th percentile – i.e., 18% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 177,745 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 36th percentile – i.e., 36% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 123 others from the same source and published within six weeks on either side of this one. This one is in the 34th percentile – i.e., 34% of its contemporaries scored the same or lower than it.