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Adjuvant Postoperative Radiotherapy to the Cervical Lymph Nodes in Cutaneous Melanoma: Is There Any Benefit for High-Risk Patients?

Overview of attention for article published in Annals of Surgical Oncology, October 2008
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Citations

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28 Mendeley
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Title
Adjuvant Postoperative Radiotherapy to the Cervical Lymph Nodes in Cutaneous Melanoma: Is There Any Benefit for High-Risk Patients?
Published in
Annals of Surgical Oncology, October 2008
DOI 10.1245/s10434-008-0087-8
Pubmed ID
Authors

Marc D. Moncrieff, Richard Martin, Christopher J. O’Brien, Kerwin F. Shannon, Jonathan R. Clark, Kan Gao, William M. McCarthy, John F. Thompson

Abstract

The use of adjuvant radiotherapy after lymph node dissection for metastatic melanoma remains controversial. This study examined the effectiveness of adjuvant radiotherapy in controlling regional disease in high-risk patients. A total of 716 patients were identified from a large prospective database who underwent cervical lymph node surgery between 1990 and 2004. Patients with high-risk disease were offered radiotherapy (n = 129), and this group was compared with the group of patients who did not receive radiotherapy (n = 587) in the same period. Radiotherapy did not improve regional control in patients who had metastatic melanoma of the cervical lymph nodes (P = .2). There were 10% fewer regional recurrences in patients with extracapsular spread who received adjuvant radiotherapy, although this was not statistically significant (P = .34). Adjuvant radiotherapy conferred no overall survival benefit to patients with nodal metastases (P = .39). There was a statistically significant trend for worse survival with increasing nodal tumor burden that remained unchanged with adjuvant radiotherapy. This large, nonrandomized retrospective study found no evidence to support the use of adjuvant radiotherapy for high-risk melanoma. A multicenter randomized, controlled trial investigating this important clinical dilemma is advocated.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 28 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Ukraine 1 4%
South Africa 1 4%
Unknown 26 93%

Demographic breakdown

Readers by professional status Count As %
Researcher 6 21%
Other 5 18%
Student > Doctoral Student 3 11%
Student > Postgraduate 3 11%
Student > Bachelor 2 7%
Other 7 25%
Unknown 2 7%
Readers by discipline Count As %
Medicine and Dentistry 20 71%
Agricultural and Biological Sciences 2 7%
Biochemistry, Genetics and Molecular Biology 1 4%
Pharmacology, Toxicology and Pharmaceutical Science 1 4%
Nursing and Health Professions 1 4%
Other 0 0%
Unknown 3 11%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 31 July 2016.
All research outputs
#7,483,725
of 22,875,477 outputs
Outputs from Annals of Surgical Oncology
#2,633
of 6,484 outputs
Outputs of similar age
#32,383
of 91,887 outputs
Outputs of similar age from Annals of Surgical Oncology
#4
of 19 outputs
Altmetric has tracked 22,875,477 research outputs across all sources so far. This one is in the 44th percentile – i.e., 44% of other outputs scored the same or lower than it.
So far Altmetric has tracked 6,484 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.4. This one is in the 46th percentile – i.e., 46% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 91,887 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 18th percentile – i.e., 18% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 19 others from the same source and published within six weeks on either side of this one. This one is in the 15th percentile – i.e., 15% of its contemporaries scored the same or lower than it.