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Gender bias in therapeutic effort: from research to health care.

Overview of attention for article published in Farmacia Hospitalaria, April 2020
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3 tweeters
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1 Facebook page

Citations

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2 Dimensions

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23 Mendeley
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Title
Gender bias in therapeutic effort: from research to health care.
Published in
Farmacia Hospitalaria, April 2020
DOI 10.7399/fh.11394
Pubmed ID
Authors

Ruiz-Cantero, María Teresa, Blasco-Blasco, Mar, Chilet-Rosell, Elisa, Peiró, Ana M, Chilet Rosell, Elisa, Peiró, Ana M., Ruiz-Cantero, María-Teresa

Abstract

There are relevant dimensions from a gender perspective related to  therapeutic effort. To illustrate and discuss possible gender bias related  to medicines, through the consumption analysis in women, the  prescription of biological drugs according to sex, the potential gender  inequality in adverse drug reactions, and research with clinical trials, as  well as the decisions of international institutions in the marketing of  medicinal products. There is greater tendency to prescribe pain  relievers, regardless of pain, and drugs for low intensity depressive  symptoms in women than in men. The opposite occurs in the  prescription of statins and adequate doses, and with the greater  probability of prescribing anti-tumor necrosis factor in men than in  women with ankylosing spondylitis, despite a similar disease burden.  Adverse drug reactions are observed more frequently in women than in  men, where determinants such as body weight are having little influence on the dosage. It is currently scarcely considered in the prescription that women have differences in the activity of cytochrome CYPP450 enzymes, which can affect the liver's metabolism rate. There  are even immunological, genetic and epigenetic effects (due to heredity  and uneven gene dosing located in the X and Y chromosomes) that can  influence these differences by sex. Finally, through cases of hormonal  therapy clinical trials, a drug for women's inhibited sexual desire and a  contraceptive for men, gender bias and stereotypes are shown to  influence a potential generation of inequalities, especially in adverse  drug reactions to the detriment of women. In conclusion, health  professionals frequently attribute physical symptoms to women's  emotionality, influencing their greater prescription of symptomatic drugs. Whether the same reason influences the lower prescription of  therapeutic drugs in women than in men should be analyzed. There are  biological determinants to consider due to their influence on a greater pharmacological toxicity in women. Clinical trials should improve  according to the gender recommendations by the Food and Drugs  Administration.

Twitter Demographics

The data shown below were collected from the profiles of 3 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 23 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 23 100%

Demographic breakdown

Readers by professional status Count As %
Student > Master 7 30%
Student > Bachelor 5 22%
Professor 1 4%
Student > Doctoral Student 1 4%
Student > Ph. D. Student 1 4%
Other 3 13%
Unknown 5 22%
Readers by discipline Count As %
Medicine and Dentistry 6 26%
Psychology 3 13%
Nursing and Health Professions 3 13%
Social Sciences 3 13%
Neuroscience 1 4%
Other 0 0%
Unknown 7 30%

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 02 February 2021.
All research outputs
#11,127,206
of 18,668,680 outputs
Outputs from Farmacia Hospitalaria
#27
of 82 outputs
Outputs of similar age
#156,084
of 297,861 outputs
Outputs of similar age from Farmacia Hospitalaria
#1
of 1 outputs
Altmetric has tracked 18,668,680 research outputs across all sources so far. This one is in the 39th percentile – i.e., 39% of other outputs scored the same or lower than it.
So far Altmetric has tracked 82 research outputs from this source. They receive a mean Attention Score of 1.9. This one has gotten more attention than average, scoring higher than 68% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 297,861 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 46th percentile – i.e., 46% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 1 others from the same source and published within six weeks on either side of this one. This one has scored higher than all of them