. Butyric acid (reduced in MS) is an anti-inflammatory short-chain fatty acid (SCFA) which promotes intestinal barrier function. Inflammatory medium-chain fatty acids (MCFA), including caproic acid (increased in MS), promote TH1 and TH17 differentiation.
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#SCFAs #microbiome Patients with multiple sclerosis had significantly lower serum concentrations of butyric acid and significantly increased caproic acid compared to controls. Caproic acid was positively associated with CD4+/IFNγ+ T lymphocytes. . https
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RT @FrontImmunol: New Research: Alterations in Circulating Fatty Acid Are Associated With Gut Microbiota Dysbiosis and Inflammation in Mult…
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New Research: Alterations in Circulating Fatty Acid Are Associated With Gut Microbiota Dysbiosis and Inflammation in Multiple Sclerosis: Background: Butyric acid (BA) is a short-chain fatty acid (SCFA) with anti-inflammatory properties, which… https://t.co