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Cytomegalovirus infection in transplant recipients

Overview of attention for article published in Clinics, July 2015
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About this Attention Score

  • In the top 5% of all research outputs scored by Altmetric
  • One of the highest-scoring outputs from this source (#6 of 1,237)
  • High Attention Score compared to outputs of the same age (99th percentile)
  • High Attention Score compared to outputs of the same age and source (92nd percentile)

Mentioned by

news
39 news outlets
blogs
1 blog
policy
1 policy source
twitter
5 X users
patent
1 patent
facebook
1 Facebook page

Citations

dimensions_citation
208 Dimensions

Readers on

mendeley
398 Mendeley
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Title
Cytomegalovirus infection in transplant recipients
Published in
Clinics, July 2015
DOI 10.6061/clinics/2015(07)09
Pubmed ID
Authors

Luiz Sergio Azevedo*, Lígia Camera Pierrotti, Edson Abdala, Silvia Figueiredo Costa, Tânia Mara Varejão Strabelli, Silvia Vidal Campos, Jéssica Fernandes Ramos, Acram Zahredine Abdul Latif, Nadia Litvinov, Natalya Zaidan Maluf, Helio Hehl Caiaffa Filho, Claudio Sergio Pannuti, Marta Heloisa Lopes, Vera Aparecida dos Santos, Camila da Cruz Gouveia Linardi, Maria Aparecida Shikanai Yasuda, Heloisa Helena de Sousa Marques

Abstract

Cytomegalovirus infection is a frequent complication after transplantation. This infection occurs due to transmission from the transplanted organ, due to reactivation of latent infection, or after a primary infection in seronegative patients and can be defined as follows: latent infection, active infection, viral syndrome or invasive disease. This condition occurs mainly between 30 and 90 days after transplantation. In hematopoietic stem cell transplantation in particular, infection usually occurs within the first 30 days after transplantation and in the presence of graft-versus-host disease. The major risk factors are when the recipient is cytomegalovirus seronegative and the donor is seropositive as well as when lymphocyte-depleting antibodies are used. There are two methods for the diagnosis of cytomegalovirus infection: the pp65 antigenemia assay and polymerase chain reaction. Serology has no value for the diagnosis of active disease, whereas histology of the affected tissue and bronchoalveolar lavage analysis are useful in the diagnosis of invasive disease. Cytomegalovirus disease can be prevented by prophylaxis (the administration of antiviral drugs to all or to a subgroup of patients who are at higher risk of viral replication) or by preemptive therapy (the early diagnosis of viral replication before development of the disease and prescription of antiviral treatment to prevent the appearance of clinical disease). The drug used is intravenous or oral ganciclovir; oral valganciclovir; or, less frequently, valacyclovir. Prophylaxis should continue for 90 to 180 days. Treatment is always indicated in cytomegalovirus disease, and the gold-standard drug is intravenous ganciclovir. Treatment should be given for 2 to 3 weeks and should be continued for an additional 7 days after the first negative result for viremia.

X Demographics

X Demographics

The data shown below were collected from the profiles of 5 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 398 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Japan 1 <1%
Brazil 1 <1%
Unknown 396 99%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 53 13%
Student > Master 51 13%
Researcher 40 10%
Student > Ph. D. Student 36 9%
Other 34 9%
Other 67 17%
Unknown 117 29%
Readers by discipline Count As %
Medicine and Dentistry 119 30%
Biochemistry, Genetics and Molecular Biology 42 11%
Immunology and Microbiology 28 7%
Agricultural and Biological Sciences 23 6%
Pharmacology, Toxicology and Pharmaceutical Science 21 5%
Other 39 10%
Unknown 126 32%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 275. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 22 December 2023.
All research outputs
#135,903
of 26,168,182 outputs
Outputs from Clinics
#6
of 1,237 outputs
Outputs of similar age
#1,288
of 279,150 outputs
Outputs of similar age from Clinics
#1
of 14 outputs
Altmetric has tracked 26,168,182 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 99th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 1,237 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 7.7. This one has done particularly well, scoring higher than 99% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 279,150 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 99% of its contemporaries.
We're also able to compare this research output to 14 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 92% of its contemporaries.