Title |
Inflammation, endothelial function and atherosclerosis in rheumatoid arthritis
|
---|---|
Published in |
Arthritis Research & Therapy, July 2012
|
DOI | 10.1186/ar3891 |
Pubmed ID | |
Authors |
Miguel A González-Gay, Carlos González-Juanatey |
Abstract |
ABSTRACT: Different techniques have proven to be useful in determining the presence of subclinical cardiovascular disease in patients with rheumatoid arthritis (RA). Doppler imaging with iontophoresis of acetylcholine and flow-mediated, endothelium-dependent vasodilation give information on endothelial dysfunction, an early step in the atherogenesis process. However, there is no good correlation between these two surrogate markers of cardiovascular disease in RA. A single determination of routine laboratory markers of inflammation does not seem to relate to endothelial function in RA. Further research is needed to determine whether microvascular endothelial function is a better predictor of cardiovascular outcome than macrovascular endothelial function in patients with RA. |
X Demographics
Geographical breakdown
Country | Count | As % |
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United States | 3 | 38% |
United Kingdom | 1 | 13% |
Unknown | 4 | 50% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 8 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Portugal | 1 | 4% |
Unknown | 24 | 96% |
Demographic breakdown
Readers by professional status | Count | As % |
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Student > Doctoral Student | 4 | 16% |
Researcher | 3 | 12% |
Student > Postgraduate | 3 | 12% |
Professor > Associate Professor | 3 | 12% |
Student > Ph. D. Student | 2 | 8% |
Other | 5 | 20% |
Unknown | 5 | 20% |
Readers by discipline | Count | As % |
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Medicine and Dentistry | 8 | 32% |
Agricultural and Biological Sciences | 4 | 16% |
Pharmacology, Toxicology and Pharmaceutical Science | 3 | 12% |
Biochemistry, Genetics and Molecular Biology | 1 | 4% |
Materials Science | 1 | 4% |
Other | 0 | 0% |
Unknown | 8 | 32% |