@johndoe90163489 @Parsifaler Here's also an interesting research: https://t.co/qme90wugw6
"#Achillesferse der infizierten Zellen" #Corona ist möglich gefunden worden The Global Phosphorylation Landscape of SARS-CoV-2 Infection https://t.co/tT3aiPpqSg
RT @BidoliNicola: @Dharmen46587056 ➡️ SC2 induces a process of Kinase (CK2) causing cellular apoptosis.👇 https://t.co/irh4fohWCt https://…
RT @fjherrmannEU: So, scientists did their job after all! August 2020 Analyzing the disease, i also ended up this being the central mechan…
The Global Phosphorylation Landscape of SARS-CoV-2 Infection https://t.co/dsgCtiQd16
RT @fjherrmannEU: So, scientists did their job after all! August 2020 Analyzing the disease, i also ended up this being the central mechan…
RT @fjherrmannEU: So, scientists did their job after all! August 2020 Analyzing the disease, i also ended up this being the central mechan…
So, scientists did their job after all! August 2020 Analyzing the disease, i also ended up this being the central mechanism. Even though i don't understand this completely; this is all anyone really needs to know: https://t.co/51BO4bwFnX
@fjherrmannEU Would be necessary to go through other symptom patterns as well. For example the Phosphorilation landscape. But it does not matter, if that fits with another mechanism. I expect there to be a number of other mechanisms involved anyway bcs of
@rkhamsi I'm not sure if it counts as big 🤣 - but I'm still kind of annoyed at my good friends for publishing this one without a preprint: https://t.co/5iEHh7ePGY
RT @lugo_ch: ➡️ La invemectina funciona con un principio similar. ➡️ También existe un fármaco experimental que regula la proporción de qui…
Cells infected with COVID-19 grow stringy, tentacle-like arms that allow the virus to invade other cells, according to a July 2020 study published in the journal Cell. Read more here: https://t.co/NCJr6gl9DC #COVID Credit: LiveScience, Cell https://t.co/le
RT @shalmida: Astonishing 🌷🌷 https://t.co/Blet6ZZkOf
RT @shalmida: Astonishing 🌷🌷 https://t.co/Blet6ZZkOf
Astonishing 🌷🌷
➡️ La invemectina funciona con un principio similar. ➡️ También existe un fármaco experimental que regula la proporción de quinasas, su nombre es 👉 Silmitasertib. ➡️ Las pruebas encontraron que este nuevo medicamento, llamado Silmitasertib, inhibe la CK2 y
549... ... ...
RT @BidoliNicola: @impressionist81 @acgarner216 @mclmat ➡️Invemectin works on a similar principle. ➡️There is also an experimental drug th…
RT @BidoliNicola: @impressionist81 @acgarner216 @mclmat ➡️Invemectin works on a similar principle. ➡️There is also an experimental drug th…
RT @macroliter: Then again.. when I see images / data like these..i feel sure AF respiratory viruses have evolved mechanisms to get airborn…
https://t.co/2St4dUt1rG "The Global Phosphorylation Landscape of SARS-CoV-2 Infection" links biophysically constrained virus-driven gain-of-function to healthy longevity across kingdoms via https://t.co/FgcC89UUiD and human endogenous retroviruses (HERVs)
@Borjetus_ @ObjetivoLaSexta @_anapastor_ Hay más estudios. https://t.co/BFQiYaY0iD
RT @QRancio: The global phosphorylation landscape of SARS https://t.co/gLS85YxDFe
The global phosphorylation landscape of SARS https://t.co/gLS85YxDFe
RT @BidoliNicola: @impressionist81 @acgarner216 @mclmat ➡️Invemectin works on a similar principle. ➡️There is also an experimental drug th…
RT @BidoliNicola: @drakchaurasia @wizofhaz @BakhleD @Psychoman53 @nightin32627875 @Dharmen46587056 ➡️Inhibiting CK2 has been found to promo…
RT @MccairnDr: @AlabasterDiadem @Parsifaler This should help clarify the matter somewhat. https://t.co/JmWlcVU9Xb https://t.co/WfdkL2C0Df
RT @MccairnDr: @AlabasterDiadem @Parsifaler This should help clarify the matter somewhat. https://t.co/JmWlcVU9Xb https://t.co/WfdkL2C0Df
RT @QRancio: Si se llama quemas agrícolas en Murcia no pasa nada, pero si se llama coronavirus se para el mundo. Hay que ver que dirigentes…
RT @QRancio: Si se llama quemas agrícolas en Murcia no pasa nada, pero si se llama coronavirus se para el mundo. Hay que ver que dirigentes…
Si se llama quemas agrícolas en Murcia no pasa nada, pero si se llama coronavirus se para el mundo. Hay que ver que dirigentes más despistados https://t.co/gLS85YPf3O
and dismantles it, in order to create vesicles in which to create its new viral RNA. What becomes of the misfolded proteins during the viral destruction of the RER? "EXTENSIVE REMODELING of the host (RER) leads to formation of double-membrane vesicles" ht
@KapiteinLukas @DamstraHugo @bewersdorflab There was this recent publication that found the accumulation of budding viral particle in filopodial protrusions. Did you have a look at that? 👇 https://t.co/jOdVdizEVQ
RT @KroganLab: In this new article, we map global phosphorylation profiles induced by #SARSCoV2 infection to kinase activities, identifying…
The "Role of Host and Pathogen-Derived MicroRNAs in Immune Regulation During Infectious and Inflammatory Diseases" has been linked to the patent for naturally occuring protonated RNA interference and healthy longevity via https://t.co/2St4dUt1rG /4
RT @mmw_lmw: The #Global_Phosphorylation Landscape of #SARSCoV2_Infection | Nevan Krogan @QBI_UCSF @CellCellPress https://t.co/gSpxei5lhx |…
RT @grosse_lab: Actin driven filopodia formation for HIV budding (paralleles to our recent findings on SARS-CoV2 and filopodia (https://t.c…
Wow, that's really fascinating stuff, the way viruses highjack the cytoskeletal machinery for their spread...
RT @grosse_lab: Actin driven filopodia formation for HIV budding (paralleles to our recent findings on SARS-CoV2 and filopodia (https://t.c…
RT @grosse_lab: Actin driven filopodia formation for HIV budding (paralleles to our recent findings on SARS-CoV2 and filopodia (https://t.c…
The Global Phosphorylation Landscape of SARS-CoV-2 Infection. https://t.co/7kz1jAgWZ9
The #Global_Phosphorylation Landscape of #SARSCoV2_Infection | Nevan Krogan @QBI_UCSF @CellCellPress https://t.co/gSpxei5lhx | #2020_ReCapAugust https://t.co/3rmlwBxX8u
RT @grosse_lab: Here is a 3D view we did of a SARS-Cov-2 infected cell displaying branched filopodia and colocalization events of N-protein…
RT @kryamamoto: Nevan Krogan, @kevansf & team discovered SARS CoV-2 rewires kinase pathways & exits via filopodia ➡️ potential COVID-19 th…
Next #phosphoproteomics 📄The Global Phosphorylation Landscape of SARS-CoV-2 Infection https://t.co/IZEibyOdKF Predicting kinases misregulated w @pedrobeltrao (10% of 500 kinases up/downregulated in COVID) Kevan Shokat "has the biggest freezer of kinase i
Researchers used GENEWIZ #Sangersequencing to reveal the rewiring of host cells' global phosphorylation by the #SARSCoV2 virus. Read the paper in @CellCellPress here: https://t.co/zNE4evmlER #BrooksLifeSciences https://t.co/0k1o8WydCC
Researchers used GENEWIZ #Sangersequencing to reveal the rewiring of host cells' global phosphorylation by the #SARSCoV2 virus. Read the paper in @CellCellPress here: https://t.co/v4hpxae1Bt #BrooksLifeSciences https://t.co/E3hnqmL48j
RT @grosse_lab: The actin nucleating Arp2/3 complex! A function for CoV-2 entry or exit or both? (see also our data on actin-rich protrusio…
RT @grosse_lab: The actin nucleating Arp2/3 complex! A function for CoV-2 entry or exit or both? (see also our data on actin-rich protrusio…
RT @grosse_lab: The actin nucleating Arp2/3 complex! A function for CoV-2 entry or exit or both? (see also our data on actin-rich protrusio…
主にリン酸化についての研究。 私はこの方面も全然分かってないので、ざっと見ただけですが、新型コロナウイルスに感染した細胞が触手を伸ばす仕組みなどにもリン酸化が関係してるそうです。 対抗薬についても調査。 Silmitasertibなどが有効そうらしい。 IC50 = 2.34 μM
RT @grosse_lab: The actin nucleating Arp2/3 complex! A function for CoV-2 entry or exit or both? (see also our data on actin-rich protrusio…
RT @grosse_lab: The actin nucleating Arp2/3 complex! A function for CoV-2 entry or exit or both? (see also our data on actin-rich protrusio…
RT @grosse_lab: The actin nucleating Arp2/3 complex! A function for CoV-2 entry or exit or both? (see also our data on actin-rich protrusio…
This pipeline of analysis has been used in recent studies such as: https://t.co/EMQXZzGsEf, highlighting the link between fibrosis, CXCL4 and inflammation https://t.co/TsRhwe2xkI, role of PDGFRb in fibrosis https://t.co/LYCoTY1pGH, TF activities after cor
RT @BrodinPetter: 4/ A number of candidate autoantibodies found elevated in MIS-C patients. Notable examples involve Casein-Kinase family m…
SARS COV 2 filopodia The Global Phosphorylation Landscape of SARSCoV-2 Infection https://t.co/8pQh8ZDfLg
RT @pedrobeltrao: How does SARS-CoV-2 take over kinase signalling to subvert normal cell function and what drugs can we use to counter thes…
The Global Phosphorylation Landscape of SARS-CoV-2 Infection https://t.co/u0p89P6hFK
[2]The Global Phosphorylation Landscape of SARS- CoV-2 Infection By Mehdi Bouhaddou, et al. Cell. August 2020 https://t.co/uY0eGzWsPu
RT @DoctorBou: Great way to visualize kinases regulated during infection as reported in our #phosphoproteomics analysis of #SARSCoV2 : http…
RT @DoctorBou: Autoantibodies to Casein Kinase 2 (CK2) found in Multisystem Inflammatory Syndrome in Children (MIS-C). How exactly do these…
RT @BrodinPetter: 4/ A number of candidate autoantibodies found elevated in MIS-C patients. Notable examples involve Casein-Kinase family m…
RT @BrodinPetter: 4/ A number of candidate autoantibodies found elevated in MIS-C patients. Notable examples involve Casein-Kinase family m…
@wvlith @RIVM_vDissel Het SARS-CoV-2 virus kan ook nog via filipodia van cel naar cel verspreiden, maar dat schijnt niet een dominante route te zijn. Maar dat is mogelijk wel een manier om het immuunsysteem te ontwijken, en snel van cel naar cel te verspre
RT @BrodinPetter: 4/ A number of candidate autoantibodies found elevated in MIS-C patients. Notable examples involve Casein-Kinase family m…
RT @BrodinPetter: 4/ A number of candidate autoantibodies found elevated in MIS-C patients. Notable examples involve Casein-Kinase family m…
RT @BrodinPetter: 4/ A number of candidate autoantibodies found elevated in MIS-C patients. Notable examples involve Casein-Kinase family m…
RT @BrodinPetter: 4/ A number of candidate autoantibodies found elevated in MIS-C patients. Notable examples involve Casein-Kinase family m…
RT @vikkypaedia: Demystifying this new inflammatory syndrome in children due to #SARSCoV2 infection... Would help in developing a more prec…
Demystifying this new inflammatory syndrome in children due to #SARSCoV2 infection... Would help in developing a more precise approach for treatment...would have been good if the research was done in collaboration with an Indian centre also..
RT @BrodinPetter: 4/ A number of candidate autoantibodies found elevated in MIS-C patients. Notable examples involve Casein-Kinase family m…
RT @DoctorBou: Autoantibodies to Casein Kinase 2 (CK2) found in Multisystem Inflammatory Syndrome in Children (MIS-C). How exactly do these…
RT @DoctorBou: Autoantibodies to Casein Kinase 2 (CK2) found in Multisystem Inflammatory Syndrome in Children (MIS-C). How exactly do these…
RT @DoctorBou: Autoantibodies to Casein Kinase 2 (CK2) found in Multisystem Inflammatory Syndrome in Children (MIS-C). How exactly do these…
RT @BrodinPetter: 4/ A number of candidate autoantibodies found elevated in MIS-C patients. Notable examples involve Casein-Kinase family m…
RT @BrodinPetter: 4/ A number of candidate autoantibodies found elevated in MIS-C patients. Notable examples involve Casein-Kinase family m…
4/ A number of candidate autoantibodies found elevated in MIS-C patients. Notable examples involve Casein-Kinase family members given recent report by @DoctorBou et al @KroganLab on upregulation of CSKII in SARS-CoV-2 infected cells: https://t.co/fofHbuErE
https://t.co/8r4FlDiiFj "If you value The Babylon Bee and want to see us prevail against Snopes and anyone else who might seek to discredit or deplatform us..." or @microRNApro see: "The Global Phosphorylation Landscape of SARS-CoV-2 Infection" https://t.c
RT @HomaMP4: The Global Phosphorylation Landscape of SARS-CoV-2 Infection https://t.co/RONq0tKm6h
The Global Phosphorylation Landscape of SARS-CoV-2 Infection https://t.co/RONq0tKm6h
The Global Phosphorylation Landscape of SARS-CoV-2 Infection https://t.co/tqRz8jfEYa https://t.co/1KrFvwYEN8
Scientist Discover Unusual Way SARS-CoV-2 Infects Other Cells Once Inside Human Host Without Need Of Receptors - @THAILANDMEDICA1 https://t.co/Zt6i5tFc1G Paper: https://t.co/jdpR2akPv3 https://t.co/If819Xhwmd
Identification of kinase inhibitors as potential #COVID19 therapeutic targets by employing time-course proteomics to map global phosphorylation profiles induced by #SARSCoV2 infection. @CellCellPress @DoctorBou @KroganLab https://t.co/a1FMLHTdJl https://t.
RT @OnLaboratory: When #COVID19 impacts on signaling pathways are deciphered! The Global Phosphorylation Landscape of #SARSCoV2 Infection.…
When #COVID19 impacts on signaling pathways are deciphered! The Global Phosphorylation Landscape of #SARSCoV2 Infection. https://t.co/X4qqpN3XQs #Cell #Covid_19 #research #science https://t.co/fUbRvb6mqY
@QBI_UCSF @UCSF @IcahnMountSinai @GladstoneInst @UniFreiburg @emblebi @HHMINEWS RT @QBI_UCSF https://t.co/NZiGXvnJDl QBI investigators and colleagues at @UCSF @IcahnMountSinai @GladstoneInst @UniFreiburg @emblebi @HHMINEWS "insights on how #SARSCoV2
Congrats to our collaborator @KroganLab A. Garcia-Sastre + huge team for phosphorylation study https://t.co/5sdrUE1EzP @CellCellPress https://t.co/j2Nm2zDMhw
Some great EM photos of filopodial protrusions loaded with viral particles. Learned about role of filopodia in cell to cell spread of SARS-CoV-2 and the translation potential of phosphoproteomics. https://t.co/VyjJwkReZg
An Easy-nLC 1200 with Nanospray Flex ion source and Orbitrap Exploris 480 #LC-#MS System, a QuantStudio 7 Flex Real-Time #PCR System and FEI BT Tecnai transmission electron microscope help to fight the #COVID-19 pandemic https://t.co/79pASLtLMm