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Salvinorin A Administration after Global Cerebral Hypoxia/Ischemia Preserves Cerebrovascular Autoregulation via Kappa Opioid Receptor in Piglets

Overview of attention for article published in PLOS ONE, July 2012
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  • Above-average Attention Score compared to outputs of the same age and source (51st percentile)

Mentioned by

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2 X users
facebook
1 Facebook page
googleplus
1 Google+ user

Citations

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25 Dimensions

Readers on

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26 Mendeley
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Title
Salvinorin A Administration after Global Cerebral Hypoxia/Ischemia Preserves Cerebrovascular Autoregulation via Kappa Opioid Receptor in Piglets
Published in
PLOS ONE, July 2012
DOI 10.1371/journal.pone.0041724
Pubmed ID
Authors

Zhenhong Wang, Nan Ma, John Riley, William M. Armstead, Renyu Liu

Abstract

Cerebral hypoxia/ischemia (HI) is not uncommon during the perinatal period. If occurring, it can result in severe neurologic disabilities that persist throughout life. Salvinorin A, a non-opioid Kappa opioid receptors (KOR) selective agonist, has the potential to address this devastating situation. We have demonstrated that salvinorin A administration before HI, preserves pial artery autoregulative function through both the KOR and extracellular signal-regulated kinases (ERK) pathways. In the present study, we tested the hypothesis that administration of salvinorin A after HI could preserve cerebral autoregulation via KOR and ERK pathway.

X Demographics

X Demographics

The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 26 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 1 4%
United States 1 4%
Unknown 24 92%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 6 23%
Researcher 6 23%
Other 3 12%
Student > Ph. D. Student 2 8%
Student > Doctoral Student 2 8%
Other 2 8%
Unknown 5 19%
Readers by discipline Count As %
Medicine and Dentistry 5 19%
Neuroscience 4 15%
Chemistry 3 12%
Agricultural and Biological Sciences 2 8%
Pharmacology, Toxicology and Pharmaceutical Science 2 8%
Other 5 19%
Unknown 5 19%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 08 September 2019.
All research outputs
#12,664,757
of 22,671,366 outputs
Outputs from PLOS ONE
#97,871
of 193,517 outputs
Outputs of similar age
#86,208
of 164,599 outputs
Outputs of similar age from PLOS ONE
#1,928
of 3,986 outputs
Altmetric has tracked 22,671,366 research outputs across all sources so far. This one is in the 43rd percentile – i.e., 43% of other outputs scored the same or lower than it.
So far Altmetric has tracked 193,517 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 15.0. This one is in the 48th percentile – i.e., 48% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 164,599 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 47th percentile – i.e., 47% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 3,986 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 51% of its contemporaries.