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X Demographics
Mendeley readers
Attention Score in Context
| Title |
CRISPR-CasΦ from huge phages is a hypercompact genome editor
|
|---|---|
| Published in |
Science, July 2020
|
| DOI | 10.1126/science.abb1400 |
| Pubmed ID | |
| Authors |
Patrick Pausch, Basem Al-Shayeb, Ezra Bisom-Rapp, Connor A Tsuchida, Zheng Li, Brady F Cress, Gavin J Knott, Steven E Jacobsen, Jillian F Banfield, Jennifer A Doudna |
| Abstract |
CRISPR-Cas systems are found widely in prokaryotes, where they provide adaptive immunity against virus infection and plasmid transformation. We describe a minimal functional CRISPR-Cas system, comprising a single ~70-kilodalton protein, CasΦ, and a CRISPR array, encoded exclusively in the genomes of huge bacteriophages. CasΦ uses a single active site for both CRISPR RNA (crRNA) processing and crRNA-guided DNA cutting to target foreign nucleic acids. This hypercompact system is active in vitro and in human and plant cells with expanded target recognition capabilities relative to other CRISPR-Cas proteins. Useful for genome editing and DNA detection but with a molecular weight half that of Cas9 and Cas12a genome-editing enzymes, CasΦ offers advantages for cellular delivery that expand the genome editing toolbox. |
X Demographics
The data shown below were collected from the profiles of 983 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 281 | 29% |
| United Kingdom | 51 | 5% |
| Germany | 34 | 3% |
| Spain | 26 | 3% |
| India | 26 | 3% |
| Australia | 25 | 3% |
| Japan | 23 | 2% |
| France | 22 | 2% |
| Canada | 21 | 2% |
| Other | 127 | 13% |
| Unknown | 347 | 35% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 544 | 55% |
| Scientists | 402 | 41% |
| Science communicators (journalists, bloggers, editors) | 20 | 2% |
| Practitioners (doctors, other healthcare professionals) | 17 | 2% |
Mendeley readers
The data shown below were compiled from readership statistics for 801 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 801 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 141 | 18% |
| Student > Ph. D. Student | 139 | 17% |
| Student > Bachelor | 82 | 10% |
| Student > Master | 64 | 8% |
| Student > Doctoral Student | 46 | 6% |
| Other | 104 | 13% |
| Unknown | 225 | 28% |
| Readers by discipline | Count | As % |
|---|---|---|
| Biochemistry, Genetics and Molecular Biology | 306 | 38% |
| Agricultural and Biological Sciences | 123 | 15% |
| Immunology and Microbiology | 25 | 3% |
| Neuroscience | 19 | 2% |
| Engineering | 15 | 2% |
| Other | 71 | 9% |
| Unknown | 242 | 30% |
Attention Score in Context
This research output has an Altmetric Attention Score of 827. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 14 March 2024.
All research outputs
#22,723
of 25,756,911 outputs
Outputs from Science
#1,055
of 83,303 outputs
Outputs of similar age
#979
of 414,717 outputs
Outputs of similar age from Science
#45
of 1,003 outputs
Altmetric has tracked 25,756,911 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 99th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 83,303 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 66.0. This one has done particularly well, scoring higher than 98% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 414,717 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 99% of its contemporaries.
We're also able to compare this research output to 1,003 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 95% of its contemporaries.