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Aldose Reductase Deficiency Reduced Vascular Changes in Neonatal Mouse Retina in Oxygen-Induced RetinopathyAR Deficiency Protects Retinal Vasculature in OIR

Overview of attention for article published in Investigative Ophthalmology & Visual Science, August 2012
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Title
Aldose Reductase Deficiency Reduced Vascular Changes in Neonatal Mouse Retina in Oxygen-Induced RetinopathyAR Deficiency Protects Retinal Vasculature in OIR
Published in
Investigative Ophthalmology & Visual Science, August 2012
DOI 10.1167/iovs.12-10122
Pubmed ID
Authors

Zhong Jie Fu, Suk-Yee Li, Norbert Kociok, David Wong, Sookja K. Chung, Amy C. Y. Lo

Abstract

Retinal neovascularization is the major pathologic process in many ocular diseases and is associated with oxidative stress. Deficiency of aldose reductase (AR), the first enzyme in the polyol pathway for glucose metabolism, has been shown to reduce oxidative stress and blood vessel leakage. The present study aimed to investigate the effect of AR deficiency on retinal neovascularization in a murine oxygen-induced retinopathy (OIR) model.

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X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 33 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
India 1 3%
Unknown 32 97%

Demographic breakdown

Readers by professional status Count As %
Student > Master 5 15%
Student > Bachelor 4 12%
Student > Ph. D. Student 4 12%
Student > Doctoral Student 3 9%
Researcher 3 9%
Other 5 15%
Unknown 9 27%
Readers by discipline Count As %
Medicine and Dentistry 8 24%
Agricultural and Biological Sciences 7 21%
Biochemistry, Genetics and Molecular Biology 4 12%
Nursing and Health Professions 1 3%
Computer Science 1 3%
Other 3 9%
Unknown 9 27%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 09 May 2013.
All research outputs
#20,656,820
of 25,374,647 outputs
Outputs from Investigative Ophthalmology & Visual Science
#6,239
of 7,983 outputs
Outputs of similar age
#146,302
of 186,119 outputs
Outputs of similar age from Investigative Ophthalmology & Visual Science
#85
of 118 outputs
Altmetric has tracked 25,374,647 research outputs across all sources so far. This one is in the 10th percentile – i.e., 10% of other outputs scored the same or lower than it.
So far Altmetric has tracked 7,983 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.1. This one is in the 12th percentile – i.e., 12% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 186,119 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 9th percentile – i.e., 9% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 118 others from the same source and published within six weeks on either side of this one. This one is in the 19th percentile – i.e., 19% of its contemporaries scored the same or lower than it.