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X Demographics
Mendeley readers
| Title |
Folate status of gut microbiome affects Caenorhabditis eleganslifespan
|
|---|---|
| Published in |
BMC Biology, July 2012
|
| DOI | 10.1186/1741-7007-10-66 |
| Pubmed ID | |
| Authors |
Theresa PT Nguyen, Catherine F Clarke |
| Abstract |
In a paper in BMC Biology Virk et al. show that Caenorhabditis elegans lifespan is extended in response to a diet of folate-deficient Escherichia coli. The deficiencies in folate biosynthesis were due to an aroD mutation, or treatment of E. coli with sulfa drugs, which are mimics of the folate precursor para-aminobenzoic acid. This study suggests that pharmacological manipulation of the gut microbiome folate status may be a viable approach to slow animal aging, and raises questions about folate supplementation. |
X Demographics
The data shown below were collected from the profiles of 5 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 2 | 40% |
| United Kingdom | 1 | 20% |
| Unknown | 2 | 40% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 3 | 60% |
| Science communicators (journalists, bloggers, editors) | 1 | 20% |
| Scientists | 1 | 20% |
Mendeley readers
The data shown below were compiled from readership statistics for 62 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 1 | 2% |
| Canada | 1 | 2% |
| Unknown | 60 | 97% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 15 | 24% |
| Student > Ph. D. Student | 11 | 18% |
| Student > Bachelor | 8 | 13% |
| Professor | 6 | 10% |
| Student > Master | 5 | 8% |
| Other | 10 | 16% |
| Unknown | 7 | 11% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 27 | 44% |
| Biochemistry, Genetics and Molecular Biology | 11 | 18% |
| Medicine and Dentistry | 4 | 6% |
| Chemistry | 4 | 6% |
| Immunology and Microbiology | 2 | 3% |
| Other | 8 | 13% |
| Unknown | 6 | 10% |