Vascular Decoupling in Septic Shock: The Combined Role of Autonomic Nervous System, Arterial Stiffness, and Peripheral Vascular Tone

@ZPutowski https://t.co/cu8CFBqt93 we've seen the same in a polymicrobial septic shock pig model.

8/10 In another animal study, resuscitation with fluids and vasopressors didn't lead to restoration of PP amplification. However, PP in radial artery mimicked PP in aorta (but not in femoral artery) - constriction by NE partially fixed PP amplification? h

4/10 Septic shock is known to impair endothelial functions, leading to an imbalance of vasodilatory and vasoconstrictive mechanisms. Large arteries increase their stiffeness, while smaller arteries increase their compliance https://t.co/kQcT6bcgPt

@Askins_Razor @nickmmark https://t.co/yAyxmb91xf