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Mis-Assembled “Segmental Duplications” in Two Versions of the Bos taurus Genome

Overview of attention for article published in PLOS ONE, August 2012
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  • Good Attention Score compared to outputs of the same age (74th percentile)
  • Good Attention Score compared to outputs of the same age and source (69th percentile)

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Title
Mis-Assembled “Segmental Duplications” in Two Versions of the Bos taurus Genome
Published in
PLOS ONE, August 2012
DOI 10.1371/journal.pone.0042680
Pubmed ID
Authors

Aleksey V. Zimin, David R. Kelley, Michael Roberts, Guillaume Marçais, Steven L. Salzberg, James A. Yorke

Abstract

We analyzed the whole genome sequence coverage in two versions of the Bos taurus genome and identified all regions longer than five kilobases (Kbp) that are duplicated within chromosomes with >99% sequence fidelity in both copies. We call these regions High Fidelity Duplications (HFDs). The two assemblies were Btau 4.2, produced by the Human Genome Sequencing Center at Baylor College of Medicine, and UMD Bos taurus 3.1 (UMD 3.1), produced by our group at the University of Maryland. We found that Btau 4.2 has a far greater number of HFDs, 3111 versus only 69 in UMD 3.1. Read coverage analysis shows that 39 million base pairs (Mbp) of sequence in HFDs in Btau 4.2 appear to be a result of a mis-assembly and therefore cannot be qualified as segmental duplications. UMD 3.1 has only 0.41 Mbp of sequence in HFDs that are due to a mis-assembly.

X Demographics

X Demographics

The data shown below were collected from the profiles of 8 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 44 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
New Zealand 2 5%
Hungary 1 2%
United States 1 2%
Belgium 1 2%
Unknown 39 89%

Demographic breakdown

Readers by professional status Count As %
Researcher 14 32%
Student > Ph. D. Student 10 23%
Student > Doctoral Student 5 11%
Student > Master 4 9%
Professor > Associate Professor 3 7%
Other 7 16%
Unknown 1 2%
Readers by discipline Count As %
Agricultural and Biological Sciences 30 68%
Biochemistry, Genetics and Molecular Biology 5 11%
Mathematics 1 2%
Environmental Science 1 2%
Computer Science 1 2%
Other 3 7%
Unknown 3 7%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 5. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 14 August 2012.
All research outputs
#6,034,570
of 22,673,450 outputs
Outputs from PLOS ONE
#72,138
of 193,525 outputs
Outputs of similar age
#42,558
of 164,736 outputs
Outputs of similar age from PLOS ONE
#1,210
of 4,050 outputs
Altmetric has tracked 22,673,450 research outputs across all sources so far. This one has received more attention than most of these and is in the 73rd percentile.
So far Altmetric has tracked 193,525 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 15.0. This one has gotten more attention than average, scoring higher than 62% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 164,736 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 74% of its contemporaries.
We're also able to compare this research output to 4,050 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 69% of its contemporaries.