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Interview-based assessment of cognition is a strong predictor of quality of life in patients with schizophrenia and severe negative symptoms

Overview of attention for article published in Revista Brasileira de Psiquiatria, June 2016
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Title
Interview-based assessment of cognition is a strong predictor of quality of life in patients with schizophrenia and severe negative symptoms
Published in
Revista Brasileira de Psiquiatria, June 2016
DOI 10.1590/1516-4446-2015-1776
Pubmed ID
Authors

Breno F. Cruz, Camilo B. de Resende, Carolina F. Carvalhaes, Clareci S. Cardoso, Antonio L. Teixeira, Richard S. Keefe, Fábio L. Rocha, João V. Salgado

Abstract

To analyze the correlation between quality of life, symptoms, and cognition assessed by the interview-based Schizophrenia Cognition Rating Scale (SCoRS). Seventy-nine outpatients diagnosed with schizophrenia were evaluated with the Quality of Life Scale - Brazilian version (QLS-BR), the SCoRS, and symptoms scales (Positive and Negative Syndrome Scale [PANSS]). After determining the potential explanatory variables using Spearman's correlation and Student's t test results, we ran simple, multivariate, and decision-tree regression analyses to assess the impact of SCoRS and PANSS ratings on mean overall quality of life. Cognitive deficits and negative symptoms were the best predictors of quality of life. A low degree of negative symptoms (PANSS negative < 11) was a strong predictor of better quality of life (QLS ∼ 75), regardless of SCoRS rating. Among participants with more severe negative symptoms, elevated cognitive impairment (interviewer SCoRS ∼ 44) was a predictor of worse quality of life (QLS ∼ 44). Cognitive impairment determined by interview-based assessment seems to be a strong predictor of quality of life in subjects with severe negative symptoms. These results support the usefulness of SCoRS for cognitive assessment that is relevant to the everyday life of patients with schizophrenia.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 74 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 1 1%
Egypt 1 1%
Unknown 72 97%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 13 18%
Student > Master 10 14%
Researcher 10 14%
Student > Ph. D. Student 10 14%
Student > Doctoral Student 3 4%
Other 14 19%
Unknown 14 19%
Readers by discipline Count As %
Psychology 23 31%
Medicine and Dentistry 13 18%
Nursing and Health Professions 5 7%
Unspecified 3 4%
Neuroscience 3 4%
Other 7 9%
Unknown 20 27%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 04 April 2017.
All research outputs
#23,154,082
of 25,806,080 outputs
Outputs from Revista Brasileira de Psiquiatria
#794
of 908 outputs
Outputs of similar age
#325,667
of 369,839 outputs
Outputs of similar age from Revista Brasileira de Psiquiatria
#8
of 9 outputs
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