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Obesity, Inflammation and Acute Myocardial Infarction - Expression of leptin, IL-6 and high sensitivity-CRP in Chennai based population

Overview of attention for article published in Thrombosis Journal, August 2012
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Title
Obesity, Inflammation and Acute Myocardial Infarction - Expression of leptin, IL-6 and high sensitivity-CRP in Chennai based population
Published in
Thrombosis Journal, August 2012
DOI 10.1186/1477-9560-10-13
Pubmed ID
Authors

Karthick Rajendran, Nalini Devarajan, Manohar Ganesan, Malathi Ragunathan

Abstract

Obesity, characterised by increased fat mass and is currently regarded as a pro-inflammatory state and often associated with increased risk of cardiovascular diseases (CVD) including Myocardial infarction. There is an upregulation of inflammatory markers such as interleukin-6, interleukin-6 receptor and acute phase protein CRP in Acute Myocardial Infarction (AMI) patients but the exact mechanism linking obesity and inflammation is not known. It is of our interest to investigate if serum leptin (ob gene product) is associated with AMI and correlated with inflammatory proteins namely Interleukin-6 (IL-6) and high sensitivity - C reactive protein (hs-CRP).

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 40 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
India 1 3%
Unknown 39 98%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 10 25%
Student > Bachelor 6 15%
Other 5 13%
Student > Doctoral Student 3 8%
Student > Master 3 8%
Other 9 23%
Unknown 4 10%
Readers by discipline Count As %
Medicine and Dentistry 14 35%
Biochemistry, Genetics and Molecular Biology 7 18%
Nursing and Health Professions 3 8%
Agricultural and Biological Sciences 3 8%
Social Sciences 2 5%
Other 6 15%
Unknown 5 13%