Title |
Obesity, Inflammation and Acute Myocardial Infarction - Expression of leptin, IL-6 and high sensitivity-CRP in Chennai based population
|
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Published in |
Thrombosis Journal, August 2012
|
DOI | 10.1186/1477-9560-10-13 |
Pubmed ID | |
Authors |
Karthick Rajendran, Nalini Devarajan, Manohar Ganesan, Malathi Ragunathan |
Abstract |
Obesity, characterised by increased fat mass and is currently regarded as a pro-inflammatory state and often associated with increased risk of cardiovascular diseases (CVD) including Myocardial infarction. There is an upregulation of inflammatory markers such as interleukin-6, interleukin-6 receptor and acute phase protein CRP in Acute Myocardial Infarction (AMI) patients but the exact mechanism linking obesity and inflammation is not known. It is of our interest to investigate if serum leptin (ob gene product) is associated with AMI and correlated with inflammatory proteins namely Interleukin-6 (IL-6) and high sensitivity - C reactive protein (hs-CRP). |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
India | 1 | 3% |
Unknown | 39 | 98% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 10 | 25% |
Student > Bachelor | 6 | 15% |
Other | 5 | 13% |
Student > Doctoral Student | 3 | 8% |
Student > Master | 3 | 8% |
Other | 9 | 23% |
Unknown | 4 | 10% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 14 | 35% |
Biochemistry, Genetics and Molecular Biology | 7 | 18% |
Nursing and Health Professions | 3 | 8% |
Agricultural and Biological Sciences | 3 | 8% |
Social Sciences | 2 | 5% |
Other | 6 | 15% |
Unknown | 5 | 13% |