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Transient Receptor Potential Ankyrin 1 Channel Localized to Non-Neuronal Airway Cells Promotes Non-Neurogenic Inflammation

Overview of attention for article published in PLOS ONE, August 2012
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Title
Transient Receptor Potential Ankyrin 1 Channel Localized to Non-Neuronal Airway Cells Promotes Non-Neurogenic Inflammation
Published in
PLOS ONE, August 2012
DOI 10.1371/journal.pone.0042454
Pubmed ID
Authors

Romina Nassini, Pamela Pedretti, Nadia Moretto, Camilla Fusi, Chiara Carnini, Fabrizio Facchinetti, Arturo Roberto Viscomi, Anna Rita Pisano, Susan Stokesberry, Charlott Brunmark, Naila Svitacheva, Lorcan McGarvey, Riccardo Patacchini, Anders B. Damholt, Pierangelo Geppetti, Serena Materazzi

Abstract

The transient receptor potential ankyrin 1 (TRPA1) channel, localized to airway sensory nerves, has been proposed to mediate airway inflammation evoked by allergen and cigarette smoke (CS) in rodents, via a neurogenic mechanism. However the limited clinical evidence for the role of neurogenic inflammation in asthma or chronic obstructive pulmonary disease raises an alternative possibility that airway inflammation is promoted by non-neuronal TRPA1.

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X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 143 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Japan 2 1%
Korea, Republic of 1 <1%
Chile 1 <1%
United Kingdom 1 <1%
United States 1 <1%
Unknown 137 96%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 31 22%
Researcher 27 19%
Student > Master 13 9%
Other 11 8%
Student > Doctoral Student 9 6%
Other 27 19%
Unknown 25 17%
Readers by discipline Count As %
Agricultural and Biological Sciences 34 24%
Medicine and Dentistry 20 14%
Biochemistry, Genetics and Molecular Biology 15 10%
Pharmacology, Toxicology and Pharmaceutical Science 13 9%
Neuroscience 11 8%
Other 15 10%
Unknown 35 24%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 14 August 2012.
All research outputs
#18,312,024
of 22,673,450 outputs
Outputs from PLOS ONE
#153,821
of 193,525 outputs
Outputs of similar age
#128,827
of 167,805 outputs
Outputs of similar age from PLOS ONE
#3,332
of 4,229 outputs
Altmetric has tracked 22,673,450 research outputs across all sources so far. This one is in the 11th percentile – i.e., 11% of other outputs scored the same or lower than it.
So far Altmetric has tracked 193,525 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 15.0. This one is in the 10th percentile – i.e., 10% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 167,805 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 10th percentile – i.e., 10% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 4,229 others from the same source and published within six weeks on either side of this one. This one is in the 8th percentile – i.e., 8% of its contemporaries scored the same or lower than it.