Title |
Azithromycin for Indigenous children with bronchiectasis: study protocol for a multi-centre randomized controlled trial
|
---|---|
Published in |
BMC Pediatrics, August 2012
|
DOI | 10.1186/1471-2431-12-122 |
Pubmed ID | |
Authors |
Patricia C Valery, Peter S Morris, Keith Grimwood, Paul J Torzillo, Catherine A Byrnes, I Brent Masters, Paul A Bauert, Gabrielle B McCallum, Charmaine Mobberly, Anne B Chang |
Abstract |
The prevalence of chronic suppurative lung disease (CSLD) and bronchiectasis unrelated to cystic fibrosis (CF) among Indigenous children in Australia, New Zealand and Alaska is very high. Antibiotics are a major component of treatment and are used both on a short or long-term basis. One aim of long-term or maintenance antibiotics is to reduce the frequency of acute pulmonary exacerbations and symptoms. However, there are few studies investigating the efficacy of long-term antibiotic use for CSLD and non-CF bronchiectasis among children. This study tests the hypothesis that azithromycin administered once a week as maintenance antibiotic treatment will reduce the rate of pulmonary exacerbations in Indigenous children with bronchiectasis. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 1 | 100% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Canada | 1 | 1% |
Unknown | 85 | 99% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Master | 14 | 16% |
Student > Ph. D. Student | 10 | 12% |
Student > Bachelor | 10 | 12% |
Researcher | 8 | 9% |
Other | 6 | 7% |
Other | 17 | 20% |
Unknown | 21 | 24% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 36 | 42% |
Pharmacology, Toxicology and Pharmaceutical Science | 7 | 8% |
Agricultural and Biological Sciences | 5 | 6% |
Biochemistry, Genetics and Molecular Biology | 2 | 2% |
Nursing and Health Professions | 2 | 2% |
Other | 12 | 14% |
Unknown | 22 | 26% |