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Bacteriophage infections of microbiota can lead to leaky gut in an experimental rodent model

Overview of attention for article published in Gut Pathogens, June 2016
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About this Attention Score

  • In the top 5% of all research outputs scored by Altmetric
  • One of the highest-scoring outputs from this source (#2 of 609)
  • High Attention Score compared to outputs of the same age (99th percentile)
  • High Attention Score compared to outputs of the same age and source (95th percentile)

Mentioned by

news
65 news outlets
blogs
2 blogs
twitter
24 X users
facebook
4 Facebook pages
googleplus
1 Google+ user
reddit
1 Redditor

Citations

dimensions_citation
70 Dimensions

Readers on

mendeley
135 Mendeley
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Title
Bacteriophage infections of microbiota can lead to leaky gut in an experimental rodent model
Published in
Gut Pathogens, June 2016
DOI 10.1186/s13099-016-0109-1
Pubmed ID
Authors

George Tetz, Victor Tetz

Abstract

Increased intestinal permeability and translocation of gut microbiota from the intestinal lumen to the systemic circulation predispose patients to various diseases and may be one of the main triggers thereof. The role of microbiota in increased intestinal permeability is under intensive investigation. Here, we studied alterations in the host and increased intestinal permeability as a direct effect of treatment with a bacteriophage cocktail. After 10 days of challenge, the rats showed weight loss, messy hair, and decreased activity. Additionally, they displayed a significantly elevated lactulose:mannitol ratio and the level of circulating immune complexes. To our knowledge, this study demonstrates for the first time that increased intestinal permeability may be induced by bacteriophages that affect the microbiota.

X Demographics

X Demographics

The data shown below were collected from the profiles of 24 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 135 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Nepal 1 <1%
United States 1 <1%
Sweden 1 <1%
France 1 <1%
Unknown 131 97%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 24 18%
Student > Ph. D. Student 20 15%
Researcher 19 14%
Student > Master 13 10%
Professor 6 4%
Other 21 16%
Unknown 32 24%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 21 16%
Immunology and Microbiology 21 16%
Agricultural and Biological Sciences 20 15%
Medicine and Dentistry 8 6%
Pharmacology, Toxicology and Pharmaceutical Science 5 4%
Other 20 15%
Unknown 40 30%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 527. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 17 March 2024.
All research outputs
#47,998
of 25,654,806 outputs
Outputs from Gut Pathogens
#2
of 609 outputs
Outputs of similar age
#965
of 369,491 outputs
Outputs of similar age from Gut Pathogens
#1
of 20 outputs
Altmetric has tracked 25,654,806 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 99th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 609 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 8.3. This one has done particularly well, scoring higher than 99% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 369,491 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 99% of its contemporaries.
We're also able to compare this research output to 20 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 95% of its contemporaries.